Minimum eliciting patch test concentrations of cobalt

Contact Dermatitis
C F Allenby, D A Basketter

Abstract

In sensitized subjects, minimum eliciting levels of cobalt were estimated using patch tests with aqueous cobalt chloride on both normal skin and on skin pretreated in various ways to enhance penetration and reactivity. 6 reacted to 10,000 ppm and 1 gave an equivocal reaction to 1000 ppm aq. cobalt. Pretreatment of the patch test site for 24 h with surfactant enhanced reactivity, reducing the minimum eliciting concentration to 1000 ppm cobalt chloride in 1 subject, to 100 ppm in 2 subjects, and in 3 subjects to 10 ppm aqueous cobalt chloride. No reactions were obtained at 1 ppm. EDTA was effective in reducing the response to aqueous cobalt.

References

Apr 1, 1988·Contact Dermatitis·J VilaplanaJ M Mascaró
Mar 1, 1987·Contact Dermatitis·J VilaplanaJ M Mascaro

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Citations

Aug 24, 1999·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·I KimberD A Basketter
Apr 16, 2002·Clinical and Experimental Dermatology·Harvey R SmithJ P McFadden
Dec 1, 1993·Journal of Toxicology and Environmental Health·A H SternF N Marzulli
Aug 24, 2010·Journal of Environmental Monitoring : JEM·Aleksandr B StefaniakGregory A Day
Jan 1, 1993·Critical Reviews in Toxicology·J J HostýnekR H Guy
Dec 7, 2007·Cutaneous and Ocular Toxicology·D A BasketterI R Jowsey
Nov 14, 2015·Contact Dermatitis·Louise A FischerJacob P Thyssen
Sep 4, 2012·The Journal of Allergy and Clinical Immunology·Julia K GittlerEmma Guttman-Yassky
Jan 13, 2016·Dermatitis : Contact, Atopic, Occupational, Drug·Joseph F Fowler
Jun 23, 2011·Contact Dermatitis·Jacob P ThyssenJeanne D Johansen
Jun 25, 2010·Contact Dermatitis·Jacob P ThyssenMorten S Jellesen
Oct 25, 2013·Contact Dermatitis·Seung Hyun CheongJi Yeon Byun
Sep 27, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Peter ThomasVera Mahler
Sep 27, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Peter ThomasVera Mahler
Feb 18, 2014·Regulatory Toxicology and Pharmacology : RTP·Beatrice BoccaGiovanni Forte
May 24, 2014·Regulatory Toxicology and Pharmacology : RTP·Marina MarinovichCorrado L Galli
Nov 13, 2017·Current Allergy and Asthma Reports·Philipp R Esser, Stefan F Martin
Feb 20, 2018·Journal of Cutaneous Medicine and Surgery·Mark G Kirchhof, Gillian C de Gannes
Jun 13, 2018·Experimental Dermatology·Ivone JakasaSanja Kezic
Sep 25, 2018·Contact Dermatitis·Anne B SimonsenJacob P Thyssen
Jul 31, 2020·Contact Dermatitis·Kotryna LinauskieneLaura Malinauskiene
Jun 21, 2001·Contact Dermatitis·R RoggebandG F Gerberick
Dec 6, 2020·Contact Dermatitis·Kotryna LinauskieneLaura Malinauskiene
Oct 17, 2009·Chemical Research in Toxicology·Jacob P Thyssen, Torkil Menné

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