Mining fatty acid databases for detection of novel compounds in aerobic bacteria

Journal of Microbiological Methods
P DawyndtJean Swings

Abstract

This study examines how the discriminatory power of an automated bacterial whole-cell fatty acid identification system can be significantly enhanced by exploring the vast amounts of information accumulated during 15 years of routine gas chromatographic analysis of the fatty acid content of aerobic bacteria. Construction of a global peak occurrence histogram based upon a large fatty acid database is shown to serve as a highly informative tool for assessing the delineation of the naming windows used during the automatic recognition of fatty acid compounds. Along the lines of this data mining application, it is suggested that several naming windows of the Sherlock MIS TSBA50 peak naming method may need to be re-evaluated in order to fit more closely with the bulk of observed fatty acid profiles. At the same time, the global peak occurrence histogram has put forward the delineation of 32 new peak naming windows, accounting for a 26% increase in the total number of fatty acid features taken into account for bacterial identification. By scrutinizing the relationships between the newly delineated naming windows and the many taxonomic units covered within a proprietary fatty acid database, all new naming windows were proven to correspo...Continue Reading

References

Oct 1, 1990·International Journal of Systematic Bacteriology·M Van den Mooter, J Swings
Jun 1, 1996·Microbiological Reviews·P VandammeJ Swings
Aug 15, 1998·Journal of Clinical Microbiology·G J OsterhoutJ D Dick
Feb 14, 2003·Systematic and Applied Microbiology·Stefanie Van TrappenJean Swings
May 15, 2004·International Journal of Systematic and Evolutionary Microbiology·Ying LiTakayuki Ezaki
Jul 29, 2004·International Journal of Systematic and Evolutionary Microbiology·Stefanie Van TrappenJean Swings
May 10, 2005·International Journal of Systematic and Evolutionary Microbiology·Olga I NedashkovskayaJean Swings

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Citations

Feb 25, 2009·Systematic and Applied Microbiology·Bram SlabbinckPaul De Vos
Jan 6, 2009·Journal of Chromatography. a·Marie HorkáKarel Slais
Nov 26, 2008·IEEE Transactions on Pattern Analysis and Machine Intelligence·Pekka MarttinenJukka Corander
Mar 15, 2011·International Journal of Systematic and Evolutionary Microbiology·Marc HeyndrickxPaul De Vos
Jan 5, 2021·Current Microbiology·Maria Juviann IsaacsCathrine Sumathi Manohar

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