Mining telemonitored physiological data and patient-reported outcomes of congestive heart failure patients

PloS One
Miha MlakarChiron and HeartMan research projects

Abstract

This paper addresses patient-reported outcomes (PROs) and telemonitoring in congestive heart failure (CHF), both increasingly important topics. The interest in CHF trials is shifting from hard end-points such as hospitalization and mortality, to softer end-points such health-related quality of life. However, the relation of these softer end-points to objective parameters is not well studied. Telemonitoring is suitable for collecting both patient-reported outcomes and objective parameters. Most telemonitoring studies, however, do not take full advantage of the available sensor technology and intelligent data analysis. The Chiron clinical observational study was performed among 24 CHF patients (17 men and 7 women, age 62.9 ± 9.4 years, 15 NYHA class II and 9 class III, 10 of ishaemic, aetiology, 6 dilated, 2 valvular, and 6 of multiple aetiologies or cardiomyopathy) in Italy and UK. A large number of physiological and ambient parameters were collected by wearable and other devices, together with PROs describing how well the patients felt, over 1,086 days of observation. The resulting data were mined for relations between the objective parameters and the PROs. The objective parameters (humidity, ambient temperature, blood pressure...Continue Reading

References

Jun 8, 2001·Bioinformatics·O TroyanskayaR B Altman
Jun 21, 2002·American Heart Journal·Stephen IulianoUNKNOWN Department of Veterans Affairs Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure
Dec 22, 2005·American Heart Journal·Tobias T LeeLana Tsao
Jul 16, 2009·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Paolo Emilio Puddu, Alessandro Menotti
Nov 17, 2010·IEEE Transactions on Bio-medical Engineering·Leandro PecchiaMarcello Bracale
May 16, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Ari GnanasakthyCatherine Copley-Merriman
Sep 27, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kathleen L GradyJames K Kirklin
Jan 31, 2013·IEEE Journal of Biomedical and Health Informatics·Evangelos B MazomenosNick Curzen
Oct 18, 2013·Journal of the Royal Society, Interface·Sidharth MaheshwariMichele Schiariti
Jan 9, 2014·International Journal of Cardiology·Christopher CookDarrel P Francis
Jan 27, 2015·European Heart Journal·Colette E JacksonUNKNOWN Meta-Analysis Global Group in Chronic Heart Failure MAGGIC
Nov 29, 2015·Annals of Global Health·James GoldieLisa Alexander
May 4, 2016·International Journal of Cardiology·G KoulaouzidisA L Clark
Dec 13, 2016·Computational and Structural Biotechnology Journal·Evanthia E TripolitiDimitrios I Fotiadis
Jan 22, 2017·Journal of Medical Internet Research·Nazli BashiDarren Walters

❮ Previous
Next ❯

Software Mentioned

HeartMan
HumAmbient
Weka
RelieF

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
Elisabete Nave-LealRui Ferreira
Journal of the American Geriatrics Society
R B BurnsM Finch
Scandinavian Cardiovascular Journal : SCJ
C M ClineB Y Israelsson
© 2022 Meta ULC. All rights reserved