PMID: 9186432Jun 1, 1997Paper

Minocycline-induced scleral pigmentation

Ophthalmology
F W Fraunfelder, J A Randall

Abstract

Minocycline is a commonly used drug in the management of acne and rosacea. Four individual cases of oral minocycline-induced scleral pigmentation are reported in the dermatologic literature. This is the first report in the ophthalmic literature and will add three new cases of probable minocycline-induced scleral pigmentation. Data on minocycline from the spontaneous reporting systems of the National Registry of Drug-Induced Ocular Side Effects, Food and Drug Administration, World Health Organization, and Lederle Laboratories were reviewed as to minocycline-related scleral pigmentation. Photographs, published cases, discussions with the examining ophthalmologists, and the personal observation of one patient (case 1) are the basis of the authors' conclusions. Seven cases of probable oral minocycline-induced scleral pigmentation are presented. These changes may or may not be associated with minocycline-induced pigmentary changes in other tissues, such as the skin, teeth, fingernails, bone, thyroid, or mucosa. The characteristic scleral pattern is a blue-gray 3- to 5-mm band starting at the limbus, which usually is enhanced in the palpebral aperture, possible due to the photosensitizing properties of the drug. Oral minocycline can ...Continue Reading

Citations

Jan 8, 2004·Journal of Cataract and Refractive Surgery·W N Charman
Jan 3, 2001·Clinics in Dermatology·D Eisen
Jan 29, 2003·Journal of Cataract and Refractive Surgery·Frederick W Fraunfelder, Larry F Rich
Dec 30, 1999·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·S Sant'AmbrogioD DiMaio
Nov 15, 2006·Cornea·Ruth Lapid-GortzakLodewijk Spanjaard
Sep 20, 2005·The British Journal of Ophthalmology·V L MorrisonB G Herndier
Oct 19, 2002·The British Journal of Ophthalmology·C ParcF D'Hermies
Nov 14, 2001·American Journal of Clinical Dermatology·O Dereure
Jan 1, 2010·Digital Journal of Ophthalmology : DJO·Isabella PhanCynthia Chiu
Aug 11, 2000·Applied Immunohistochemistry & Molecular Morphology : AIMM·R KorenR Gal
Sep 9, 2015·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Michael J Doughty
Nov 22, 2016·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Cheryl HaskesDavid Imondi
Oct 31, 2018·American Journal of Clinical Dermatology·Amanda F NahhasIltefat H Hamzavi
Jun 1, 2000·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·P LangevitzM Pras
Sep 26, 2000·Oral Diseases·J P HuT Yamada
May 24, 2003·La Revue de médecine interne·L GrassetM Ollagnier

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