Minor digestive symptoms and their impact in the general population: a cluster analysis approach

Therapeutic Advances in Gastroenterology
Diane L'Heureux-BouronP J Whorwell

Abstract

The classification and treatment of patients who do not meet the criteria for a functional gastrointestinal (GI) disorder has not been well established. This study aimed to record the prevalence of minor digestive symptoms (MDSs) in the general population attempting to divide them into symptom clusters as well as trying to assess their impact and the way sufferers cope with them. Following face-to-face interviews, a web-based, self-administered questionnaire was designed to capture a range of GI sensations using 34 questions and 12 images depicting abdominal symptoms. A randomly selected sample of 1515 women and 409 men representing the general population in France was studied. Cluster analysis was used to identify groups of respondents with naturally co-occurring symptoms. Data were also collected on other factors such as exacerbating and relieving strategies. MDSs were reported at least every 2 months in 66.5% of women and 47.7% of men. A total of 11 symptom clusters were identified: constipation-like, flatulence, abdominal pressure, abdominal swelling, acid reflux, diarrhoea-like, intestinal heaviness, intestinal pain, gurgling, burning and gastric pain. Despite being minor, these problems had a major impact on vitality and ...Continue Reading

References

Sep 2, 1978·British Medical Journal·A P ManningA F Morris
Jul 11, 1998·Alcoholism, Clinical and Experimental Research·D B HillS Barve
Aug 25, 2004·Best Practice & Research. Clinical Gastroenterology·Enrico Corazziari
Nov 4, 2004·Alimentary Pharmacology & Therapeutics·L Chang
Apr 12, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·George F Longstreth, Douglas A Drossman
Jun 4, 2005·Alimentary Pharmacology & Therapeutics·A P S HunginV Barghout
Jun 14, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael CamilleriDennis A Revicki
May 9, 2006·Gastroenterology·Douglas A Drossman
May 9, 2006·Gastroenterology·George F LongstrethRobin C Spiller
Feb 13, 2008·Scandinavian Journal of Gastroenterology·Mark T EltringhamYan Yiannakou
Apr 18, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N J Talley
Feb 24, 2009·The International Journal of Clinical and Experimental Hypnosis·Helen R CarruthersPeter J Whorwell
May 7, 2009·The Annals of Pharmacotherapy·Els MehuysDanny De Looze
May 20, 2009·Scandinavian Journal of Gastroenterology·Maureen WiesnerJohn O Hunter
Sep 12, 2009·Alimentary Pharmacology & Therapeutics·H R CarruthersP J Whorwell
May 29, 2010·Palliative Medicine·Aynur AktasLisa Rybicki
Mar 31, 2011·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·L Van OudenhoveJ Tack
Apr 8, 2011·World Journal of Gastroenterology : WJG·Philip G DinningIan J Cook
May 24, 2011·Journal of Neurogastroenterology and Motility·Yukari TanakaDouglas A Drossman
Sep 22, 2011·Current Opinion in Gastroenterology·Jan TackPieter Janssen
Sep 10, 2014·Alimentary Pharmacology & Therapeutics·C CanavanT Card
Dec 20, 2014·Scandinavian Journal of Gastroenterology·Sanne RasmussenDorte Ejg Jarbøl
May 6, 2016·Gastroenterology·Douglas A Drossman, William L Hasler

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Citations

Aug 3, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Mario García-CarrascoMax Schmulson

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Methods Mentioned

BETA
MDSs
MDS

Software Mentioned

Viewsnet
Synovate SAS
Daisy
ADN

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