Minute ventilation assessment in the PACU is useful to predict postoperative respiratory depression following discharge to the floor: A prospective cohort study

Journal of Clinical Anesthesia
Roman SchumannIwona Bonney

Abstract

Reliably identifying patients at risk for postoperative respiratory depression (RD) remains an unmet need. We hypothesized that defined low minute ventilation events (LMVe) near the end of the post-anesthesia care unit (PACU) stay identifies patients at RD risk on the general hospital floor (GHF). Prospective observational study. Tertiary care, urban academic medical center. PACU and GHF during the first postoperative night. One hundred-and-nineteen adult, ASA I - III patients undergoing elective surgery under general anesthesia completed the study. Data collection from a non-invasive respiratory volume monitor and the patients' medical record perioperatively through the first postoperative night. Minute ventilation (MV), tidal volume (TV) and respiratory rate (RR) were measured continuously in the PACU and on the GHF. MV was counted as the percent of individual predicted MV (MVPRED), and RD was defined as ≥1 LMVe/h on the GHF. Based on the number of LMVes within 30 min before PACU discharge, patients were grouped into A, 'Not-At-Risk': 0 LMVe and B, 'At-Risk': ≥1 LMVes. Unpaired t-test, Mann-Whitney U test, ANOVA, Kruskal-Wallis test, Fisher's exact test, sensitivity and specificity and ROC curve analyses were applied as appro...Continue Reading

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Citations

Jan 26, 2020·Journal of Clinical Monitoring and Computing·D S KarbingM B Jaffe
Jul 12, 2020·Aging Clinical and Experimental Research·Paola AcetoUNKNOWN Società Italiana di Anestesia Analgesia Rianimazione e Terapia Intensiva (SIAARTI), Società Italiana di Gerontologia e Geria
Aug 7, 2021·Critical Care : the Official Journal of the Critical Care Forum·Oscar F C van den BoschStephan A Loer

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