miR-193: A new weapon against cancer

Journal of Cellular Physiology
Monireh KhordadmehrBehzad Baradaran

Abstract

microRNAs (miRNAs) are known as a large group of short noncoding RNAs, which structurally consist of 19-22 nucleotides in length and functionally act as one of the main regulators of gene expression in important biological and physiological contexts like cell growth, apoptosis, proliferation, differentiation, movement (cell motility), and angiogenesis as well as disease formation and progression importantly in cancer cell invasion, migration, and metastasis. Among these notable tiny molecules, many studies recently presented the important role of the miR-193 family comprising miR-193a-3p, miR-193a-5p, miR-193b-3p, and miR-193b-5p in health and disease biological processes by interaction with special targeting and signaling, which mainly contribute as a tumor suppressor. Therefore, in the present paper, we review the functional role of this miRNA family in both health and disease conditions focusing on various tumor developments, diagnoses, prognoses, and treatment.

References

Sep 2, 1999·Carcinogenesis·D M OwensR C Smart
Aug 4, 2006·Cancer Research·George Adrian Calin, Carlo Maria Croce
Oct 25, 2006·Nature Reviews. Cancer·George A Calin, Carlo M Croce
Dec 13, 2006·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·A SalviG De Petro
Apr 17, 2007·Nature Genetics·Idoya LahortigaJan Cools
Dec 7, 2007·Cancer Research·Joanne B WeidhaasFrank J Slack
Jul 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Patrick S MitchellMuneesh Tewari
Sep 6, 2008·PloS One·Shlomit GiladAyelet Chajut
Sep 9, 2008·Journal of the American Society of Nephrology : JASN·Shaolin ShiErwin P Bottinger
Sep 18, 2009·The Journal of Investigative Dermatology·Enikö SonkolyAndor Pivarcsi
Jan 15, 2010·International Journal of Cancer. Journal International Du Cancer·Hanna E RauhalaTapio Visakorpi
Mar 23, 2010·The American Journal of Pathology·Jiamin ChenVictor A Tron
Apr 2, 2010·The Journal of Investigative Dermatology·Stefano CaramutaWeng-Onn Lui
Jun 1, 2010·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Xiaobin LuoZhiguo Wang
Jul 27, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Chengwang XuXiaofei Zheng
Sep 10, 2010·The Journal of Investigative Dermatology·Janosch HildebrandAnja Knott
Mar 23, 2011·Translational Research : the Journal of Laboratory and Clinical Medicine·Rujuan Dai, S Ansar Ahmed
Apr 5, 2011·Mutation Research·Maria I AlmeidaGeorge A Calin
Jul 5, 2011·Asia-Pacific Journal of Public Health·Janine DukeSuzanne Rea
Jul 9, 2011·American Journal of Physiology. Gastrointestinal and Liver Physiology·Michael Papetti, Leonard H Augenlicht
Jul 12, 2011·Nature Cell Biology·Lei SunHarvey F Lodish
Aug 23, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ying-Jie GuanQian Chen
Sep 7, 2011·The American Journal of Pathology·Jiamin ChenVictor A Tron
Oct 14, 2011·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Biqiang ZhengYingqiang Shi
Nov 2, 2011·The Breast : Official Journal of the European Society of Mastology·Marilena V IorioElda Tagliabue
Dec 23, 2011·Molecular Cancer Research : MCR·Yushi IkedaToru Furukawa
Jan 28, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Gerwin HellerSabine Zöchbauer-Müller
Feb 16, 2012·Molecular Systems Biology·Stefan UhlmannOzgür Sahin
Mar 3, 2012·Medicinal Research Reviews·Ke Zen, Chen-Yu Zhang
Apr 12, 2012·Acta Biochimica Et Biophysica Sinica·Huajun HuBin Ni
Jun 8, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Taku UkaiJoji Mochida
Jul 7, 2012·PloS One·Simona GrecoFabio Martelli

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Citations

Sep 5, 2020·BMJ Open Diabetes Research & Care·Hyoshik KimSoon Hyo Kwon
Sep 3, 2020·Cell Biology and Toxicology·Yuanming JingZongliang Huang
Sep 2, 2020·International Journal of Molecular Sciences·Beatrice PoliniPaola Nieri
Dec 12, 2020·Annals of Clinical Biochemistry·Yan HongKaiyue Zhang
Jan 7, 2020·Immunology Letters·Roya ShahbaziHamed Ezzati
Dec 24, 2020·Journal of Cellular and Molecular Medicine·Chang CaoJinying Zhang
Mar 6, 2021·Molecular Therapy. Nucleic Acids·Marion T J van den BoschMichel Janicot
Jun 18, 2021·International Immunopharmacology·Baoyi YinGanzhen Deng
Jul 3, 2021·International Journal of Molecular Sciences·Adriana FodorAngela Cozma

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