Mirror neuron therapy for hemispatial neglect patients

Scientific Reports
Wei WangChunlei Shan

Abstract

Mirror neuron system(MNS) based therapy has been employed to treat stroke induced movement disorders. However, its potential effects on patients with hemispatial neglect were uninvestigated. The present study set out to test the therapeutic efficiency of video watching of series of hand actions/movements (protocol A) in two patients with left hemispatial neglect, due to the right hemisphere stroke. The video containing dynamic landscape of natural scene or cities but not human/animals was used as the protocol B. The "ABA" training procedure for 3 weeks therefore allows us to internally control the individual differences. Before and after each week of training, the Chinese behavioral inattention test- Hongkong version (CBIT-HK) was implemented to evaluate the hemispatial neglect severity. Functional magnetic resonance imaging (fMRI) experiment was implemented in two health subjects to reveal the difference of brain activation between protocol A and B. The results showed that protocol A rather than protocol B significantly improved the CBIT-HK scores at first and third weeks, respectively. Protocol A induced more bilateral activations including right inferior parietal lobe (supramarginal gyrus), which belongs to MNS and is also c...Continue Reading

References

Mar 1, 1997·American Journal of Physical Medicine & Rehabilitation·P M PedersenT S Olsen
Mar 18, 2003·Trends in Cognitive Sciences·Peter W. HalliganGiuseppe Vallar
Jun 25, 2003·Brain : a Journal of Neurology·Dominic J MortMasud Husain
Jun 26, 2004·Annual Review of Neuroscience·Giacomo Rizzolatti, Laila Craighero
Jan 17, 2007·Journal of Rehabilitation Medicine·Sjoerd de Vries, Theo Mulder
Aug 28, 2007·Annals of Neurology·Marco Iacoboni, John C Mazziotta
Oct 5, 2010·Neuropsychologia·Paola MarangoloAnna Cantagallo
Mar 15, 2012·Developmental Psychobiology·Steven L SmallAna Solodkin
Nov 13, 2013·Nature Reviews. Neurology·Steven L SmallAna Solodkin

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Citations

Jul 24, 2018·Evaluation & the Health Professions·Vilma FerreiraKarina Tamy Kasawara
Sep 26, 2020·Disability and Rehabilitation·Chuka UmeonwukaVeronica Ntsiea
Sep 25, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Yuqian ZhangYulong Bai

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