Mitigation of pandemic influenza: review of cost-effectiveness studies

Expert Review of Pharmacoeconomics & Outcomes Research
Anna K Lugnér, Maarten J Postma

Abstract

We conducted a review of economic evaluations of pandemic influenza control measures. In the studies found, we detected various interventions being investigated: antiviral stockpiling and treatment, prophylaxis, vaccination, school closure and restricting international travel. Cost-effectiveness varied but often showed potentials for the favorable economic profiles of these measures. Both static and dynamic models were used. We conclude that the choice of an appropriate model - in particular, a dynamic model - is crucial to arrive at valid cost-effectiveness ratios. Yet, of the economic evaluations considered here, only a few were based on dynamic modeling. We recommend that further research is directed toward linking dynamic epidemiological models for pandemic spread with economic outcomes by considering the full impacts on national economies, including direct, indirect, medical and nonmedical costs.

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Citations

Feb 25, 2011·PLoS Computational Biology·T Déirdre HollingsworthRoy M Anderson
Jan 4, 2013·Bulletin of the World Health Organization·Tom L DrakeRichard Coker
Dec 8, 2010·Expert Review of Anti-infective Therapy·Maarten J PostmaUNKNOWN PI Group
Jul 26, 2012·Expert Review of Vaccines·Maarten J Postma
Mar 17, 2015·The Lancet. Respiratory Medicine·Andreas Handel, Mark H Ebell
Nov 20, 2020·Scientific Reports·C NeuwirthT Murphy
Aug 28, 2021·Healthcare·Kang-Hua CaoJay Zarnikau

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