PMID: 8937831Oct 1, 1996Paper
Mitochondria, free radicals, and neurodegeneration
Current Opinion in Neurobiology
M F Beal
Abstract
A central role for defective mitochondrial energy production, and the resulting increased levels of free radicals, in the pathogenesis of various neurodegenerative diseases is gaining increasing acceptance. Defects in energy metabolism may contribute to both excitotoxicity and oxidative damage. Evidence implicating energy defects in neurodegenerative diseases comes from similarities to known mitochondrial disorders, including delayed and variable age of onset, slow progression, and symmetric degeneration of circumscribed groups of neurons.
References
Nov 1, 1992·Archives of Biochemistry and Biophysics·H IschiropoulosJ S Beckman
Oct 27, 1989·Science·M P King, G Attardi
Nov 1, 1995·Neurology·A M PennW R Martin
May 4, 1995·Nature·J F CollardJ P Julien
Jun 1, 1995·Neuron·P C WongD L Price
Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·E BrouilletM F Beal
Apr 13, 1995·Nature·L MedaF Rossi
Jun 1, 1995·Annals of Neurology·H M SchipperE G Stopa
Jan 31, 1995·Proceedings of the National Academy of Sciences of the United States of America·M E RippsJ W Gordon
Mar 10, 1995·Cell·R H Brown
Aug 2, 1994·Proceedings of the National Academy of Sciences of the United States of America·S D YanM A Smith
Jun 17, 1994·Science·M E GurneyH X Deng
Dec 1, 1993·Neurology·B G JenkinsB R Rosen
Jul 22, 1993·Nature·D R Rosen
Dec 21, 1995·Nature·J Busciglio, B A Yankner
Jan 26, 1996·Science·M Wiedau-PazosD E Bredesen
Jan 1, 1996·Neuron·J HerringtonB Hille
Mar 14, 1996·Nature·T ThomasM Mullan
Mar 1, 1996·Annals of Neurology·M GuA H Schapira
Apr 2, 1996·Proceedings of the National Academy of Sciences of the United States of America·A YoritakaY Mizuno
Apr 2, 1996·Proceedings of the National Academy of Sciences of the United States of America·P H TuV M Lee
Mar 1, 1996·Nature Medicine·J R BurkeW J Strittmatter
Mar 15, 1996·Archives of Biochemistry and Biophysics·R M UppuW A Pryor
Apr 16, 1996·Proceedings of the National Academy of Sciences of the United States of America·S K KongP B Chock
May 14, 1996·Proceedings of the National Academy of Sciences of the United States of America·S PrzedborskiT M Dawson
Mar 5, 1996·Proceedings of the National Academy of Sciences of the United States of America·C SzabóA L Salzman
Mar 5, 1996·Proceedings of the National Academy of Sciences of the United States of America·B S BerlettE R Stadtman
Sep 1, 1996·Nature Medicine·P HantrayeM F Beal
Feb 1, 1996·Neuron·M PatelJ O McNamara
Oct 1, 1996·Annals of Neurology·R H SwerdlowW D Parker
Feb 2, 1996·Neuroscience Letters·S Sasaki, M Iwata
Feb 1, 1996·Annals of Neurology·M E GurneyE D Hall
Feb 1, 1996·Annals of Neurology·L SiklósS H Appel
❮ Previous
Next ❯
Citations
Jun 16, 1999·Journal of Neuroscience Research·Q GuoM P Mattson
May 8, 2000·Journal of Neuroscience Research·I Velasco, R Tapia
May 19, 2001·Annals of Neurology·K L Quick, L L Dugan
Oct 20, 1998·Annals of Neurology·M SchuelkeA von Moers
Dec 18, 2001·Journal of Neuroscience Research·L C ParkG E Gibson
Jul 12, 2002·Journal of Neuroscience Research·Paula I MoreiraCatarina Oliveira
Nov 9, 2000·Analytical Biochemistry·C JungZ Xu
Jan 1, 1997·Journal of Neural Transmission·S Bano, M S Parihar
Jan 4, 2012·Journal of Neural Transmission·Mahesh Ramalingam, Sung-Jin Kim
Mar 31, 2011·Amino Acids·M Flint Beal
Oct 16, 2009·Journal of Bioenergetics and Biomembranes·Cristina CarvalhoGeorge Perry
Apr 25, 2012·Metabolic Brain Disease·Sharief HendricksVivienne A Russell
Nov 14, 2008·Neuromolecular Medicine·Peter J Adhihetty, M Flint Beal
Aug 25, 2012·Neurotoxicity Research·Deep Raj SharmaKiran Dip Gill
Jun 19, 2013·Brain Research·Nicola J RutherfordBenoit I Giasson
Mar 24, 2004·Chemistry and Physics of Lipids·L Jackson Roberts, Joshua P Fessel
Aug 9, 2005·Free Radical Biology & Medicine·Anuradha DhanasekaranB Kalyanaraman
Oct 14, 2003·Biochemical Pharmacology·Anne EckertWalter E Müller
Jan 16, 1999·Biochemical Pharmacology·T Jabs
Apr 7, 2000·Brain Research·R GarridoM Toborek
May 29, 2000·Brain Research·K TsuboiC W Shults
Nov 26, 2002·Brain Research·Alexandra LatiniMoacir Wajner
Jan 29, 2000·Brain Research·M MartínezN Martínez
Dec 31, 2002·Life Sciences·H BaranH Nohl
Mar 18, 2003·Life Sciences·A RussoM Renis
Nov 27, 1999·Life Sciences·D A ButterfieldJ M Carney
Jun 19, 2001·Neuropharmacology·Y Gilgun-SherkiD Offen
Feb 5, 2003·Neurotoxicology·Gabriele SchmuckMartin Kayser
Mar 14, 2001·Brain Research. Brain Research Reviews·A LawR Quirion
Apr 30, 2002·Brain Research. Molecular Brain Research·Tom GrammatopoulosJames Weyhenmeyer
Dec 12, 2001·Neurochemistry International·Mathieu LesortGail V W Johnson
Dec 12, 2001·Neurochemistry International·Soo Youl KimPeter M Steinert
Oct 24, 2002·Neurobiology of Aging·Ennio EspositoSergio Algeri
Jul 14, 1998·Neurobiology of Aging·N C Berchtold, C W Cotman
Apr 5, 2000·Progress in Neurobiology·M LesortG V Johnson
Jul 25, 2000·Neuroscience Letters·A BoireauS Moussaoui
Jun 6, 1997·Neuroscience Letters·D W ZochodneH Sun
Apr 20, 2001·Neuroscience·L RossiM R Ciriolo
Jul 3, 1999·Neuroscience·D W ZochodneM Lauritzen
May 6, 1999·Brain Research Bulletin·O P Mishra, M Delivoria-Papadopoulos
Jul 27, 2001·Journal of Chemical Neuroanatomy·S BahnP C Emson
Mar 4, 2000·Journal of Chemical Neuroanatomy·Y H CheM Tohyama
Aug 6, 2000·Free Radical Biology & Medicine·J C CopinP H Chan
Mar 29, 2001·Free Radical Biology & Medicine·I Le Foll, D P Duval
Sep 5, 2002·Free Radical Biology & Medicine·Ulf T Brunk, Alexei Terman
Jan 21, 2000·Free Radical Biology & Medicine·I Cantuti-Castelvetri, J A Joseph
Mar 21, 2002·Epilepsy Research·Hannah R CockMatthew C Walker
Apr 24, 1999·The Journal of Steroid Biochemistry and Molecular Biology·J Zheng, V D Ramirez
Oct 24, 2003·Molecular and Cellular Neurosciences·Yasuyuki IshikawaHiroshi Hatanaka
Oct 13, 2000·British Journal of Pharmacology·Y SagotA C Kato
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