PMID: 13549500May 25, 1958Paper

Mitochondria isolated from rat brown adipose tissue and liver

The Journal of Biophysical and Biochemical Cytology
J D LEVER, J B CHAPPELL

Abstract

Mitochondrial fractions, relatively free from contamination by other cytoplasmic structures, have been isolated by differential centrifugation from homogenates of brown adipose tissue from starved rats. It was possible in such fractions to distinguish two types of mitochondria in this tissue. Type I mitochondria, when morphologically intact, are limited by a bilaminar membrane and show regular parallel cristae. In isolated fractions, a proportion of these mitochondria are swollen, vacuolation occurring within the cristae between their limiting membranes. Type II mitochondria are distinguished from the more numerous type I bodies by the opaque appearance of their matrix. They are limited by a membrane which is in part single, and in part double. They show a few, but crisply outlined internal membranes. Vacuolation of this type of mitochondrion has not been observed. Vacuolation comparable to that in brown fat mitochondria was also observed between the two laminae of the enclosing membrane and within the cristae of liver mitochondria.

References

Nov 25, 1956·The Journal of Biophysical and Biochemical Cytology·P SIEKEVITZ, M L WATSON

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Citations

Jan 1, 1960·Zeitschrift für Zellforschung und mikroskopische Anatomie·D DUNCAN, W HILD
Jun 1, 1968·Comparative Biochemistry and Physiology·J F ThompsonD A Habeck
Oct 1, 1962·The Journal of Cell Biology·M N Berry, F O Simpson
Oct 1, 1959·The Journal of Biophysical and Biochemical Cytology·H TEDESCHI
Jul 1, 1960·The Journal of Biophysical and Biochemical Cytology·H PAULY, L PACKER
Mar 23, 2013·Diabetes·Christopher G R PerryP Darrell Neufer
Sep 1, 1958·J R Microsc Soc·P R LEWIS, J D LEVER
Mar 22, 2019·Nature Communications·Luca ScorranoMaya Schuldiner
Mar 29, 2018·Biochemical Society Transactions·Francesca Giordano
Jul 7, 2020·Frontiers in Cell and Developmental Biology·Lingna XuChao Tong
Nov 5, 2020·International Journal of Molecular Sciences·Flavia GiamoganteTito Calì
Dec 3, 2020·Frontiers in Physiology·Brian GlancyT Bradley Willingham
Mar 7, 2021·Biomedicines·Nuno Santos Leal, Luís Miguel Martins

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