Mitochondrial contributions to neuronal development and function.

Biological Chemistry
Andrea PrinczNektarios Tavernarakis

Abstract

Mitochondria are critical to tissues and organs characterized by high-energy demands, such as the nervous system. They provide essential energy and metabolites, and maintain Ca2+ balance, which is imperative for proper neuronal function and development. Emerging findings further underline the role of mitochondria in neurons. Technical advances in the last decades made it possible to investigate key mechanisms in neuronal development and the contribution of mitochondria therein. In this article, we discuss the latest findings relevant to the involvement of mitochondria in neuronal development, placing emphasis on mitochondrial metabolism and dynamics. In addition, we survey the role of mitochondrial energy metabolism and Ca2+ homeostasis in proper neuronal function, and the involvement of mitochondria in axon myelination.

References

Mar 6, 2002·Journal of Neurophysiology·Kathryn Medler, Evanna L Gleason
Jun 29, 2002·Nature Neuroscience·Alexander V PanovJ Timothy Greenamyre
Dec 3, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jarin HongpaisanS Brian Andrews
Feb 1, 2005·Cell·Daniele BanoPierluigi Nicotera
Apr 29, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marat V AvshalumovMargaret E Rice
Feb 3, 2006·Molecular Biology of the Cell·Alexandra BenchouaEmmanuel Brouillet
Sep 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·Alberto FerriMaria Teresa Carrì
Dec 26, 2006·Progress in Neurobiology·Mannie M Y Fan, Lynn A Raymond
Jan 24, 2007·Acta Neuropathologica·Andrew P MizisinG Diane Shelton
Feb 6, 2007·Biophysical Journal·Sergej L Mironov
Jul 10, 2007·Biochimica Et Biophysica Acta·Wenzhi Tan, Marco Colombini
Aug 24, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Laura FerraiuoloPamela J Shaw
Sep 4, 2007·Cell Calcium·Kenneth W YoungPierluigi Nicotera
Dec 22, 2007·Nature Reviews. Molecular Cell Biology·Richard J Youle, Andreas Strasser
Dec 25, 2007·The Journal of Biological Chemistry·Dmitry LimErnesto Carafoli
Mar 13, 2008·The Journal of Biological Chemistry·Marjatta SonJeffrey L Elliott
Apr 22, 2008·IUBMB Life·Danielle J SmithPhillip Nagley
Oct 11, 2008·Cell Death and Differentiation·G KroemerUNKNOWN Nomenclature Committee on Cell Death 2009
Mar 21, 2009·Biochimica Et Biophysica Acta·David G Nicholls
Apr 22, 2009·The International Journal of Biochemistry & Cell Biology·Sergei L Mironov
Jun 24, 2009·BMC Neuroscience·Manoj Kumar JaiswalBernhard U Keller
Sep 16, 2009·Biochimica Et Biophysica Acta·Phillip NagleyPhilip M Beart
Sep 16, 2009·The Journal of Cell Biology·Junko WakabayashiHiromi Sesaki
Nov 10, 2009·Cell Stem Cell·Valérie M RenaultAnne Brunet
Nov 10, 2009·Cell Stem Cell·Ji-hye PaikRonald A DePinho
Dec 19, 2009·Proceedings of the National Academy of Sciences of the United States of America·Raz PaltyIsrael Sekler
May 28, 2011·Brain : a Journal of Neurology·Gigi J EbenezerMichael Polydefkis
Jul 15, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Andreu ViaderJeffrey Milbrandt

❮ Previous
Next ❯

Methods Mentioned

BETA
GTPase
transgenic

Related Concepts

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.

Related Papers

Seikagaku. The Journal of Japanese Biochemical Society
Jin Nakahara, Hiroaki Asou
Archivio Italiano Di Anatomia E Di Embriologia. Italian Journal of Anatomy and Embryology
P Del Grande, A Quaglia
© 2022 Meta ULC. All rights reserved