Mitochondrial DNA reveals distinct evolutionary histories for Jewish populations in Yemen and Ethiopia

American Journal of Physical Anthropology
Amy NonConnie J Mulligan

Abstract

Southern Arabia and the Horn of Africa are important geographic centers for the study of human population history because a great deal of migration has characterized these regions since the first emergence of humans out of Africa. Analysis of Jewish groups provides a unique opportunity to investigate more recent population histories in this area. Mitochondrial DNA is used to investigate the maternal evolutionary history and can be combined with historical and linguistic data to test various population histories. In this study, we assay mitochondrial control region DNA sequence and diagnostic coding variants in Yemenite (n = 45) and Ethiopian (n = 41) Jewish populations, as well as in neighboring non-Jewish Yemeni (n = 50) and Ethiopian (previously published Semitic speakers) populations. We investigate their population histories through a comparison of haplogroup distributions and phylogenetic networks. A high frequency of sub-Saharan African L haplogroups was found in both Jewish populations, indicating a significant African maternal contribution unlike other Jewish Diaspora populations. However, no identical haplotypes were shared between the Yemenite and Ethiopian Jewish populations, suggesting very little gene flow between ...Continue Reading

References

Jan 1, 1977·Culture, Medicine and Psychiatry·A Young
Feb 1, 1997·Genetics·S TavaréP Donnelly
Jan 9, 1999·American Journal of Physical Anthropology·M M Lahr, R A Foley
May 20, 1999·Molecular Biology and Evolution·H J BandeltA Röhl
Nov 27, 1999·Current Biology : CB·T KivisildR Villems
May 16, 2000·Nature·C Stringer
Oct 18, 2000·American Journal of Human Genetics·M RichardsH J Bandelt
Dec 29, 2000·Nature·M IngmanU Gyllensten
Jan 2, 2003·Proceedings of the National Academy of Sciences of the United States of America·Dan MishmarDouglas C Wallace
Mar 12, 2003·American Journal of Human Genetics·Martin RichardsAntonio Torroni
Aug 21, 2003·Molecular Phylogenetics and Evolution·N Al-ZaheryA S Santachiara-Benerecetti
Feb 12, 2004·American Journal of Human Genetics·Antonio SalasAngel Carracedo
Jan 13, 2006·American Journal of Human Genetics·Doron M BeharKarl Skorecki
May 9, 2006·Trends in Genetics : TIG·Antonio TorroniHans-Jürgen Bandelt
May 17, 2006·Proceedings of the National Academy of Sciences of the United States of America·Elise M S BelleGuido Barbujani
May 19, 2006·International Journal of Legal Medicine·A PicornellM M Ramon
Mar 3, 2007·BMC Evolutionary Biology·Khaled K Abu-AmeroVicente M Cabrera
Oct 12, 2007·European Journal of Human Genetics : EJHG·Alicia M CadenasRene J Herrera
Feb 8, 2008·American Journal of Physical Anthropology·Viktor CernýLuísa Pereira
Apr 29, 2008·American Journal of Human Genetics·Doron M BeharUNKNOWN Genographic Consortium
Jun 9, 2009·American Journal of Human Genetics·Pedro SoaresMartin B Richards
Aug 18, 2009·Trends in Ecology & Evolution·Phillip EndicottChris Stringer

❮ Previous
Next ❯

Citations

Nov 23, 2011·Genome Biology·Vincenza ColonnaChris Tyler-Smith
Jun 13, 2014·PLoS Genetics·Jason A HodgsonRyan L Raaum
Jan 1, 2015·Evolutionary Bioinformatics Online·Saioa LópezGarrett Hellenthal
Feb 17, 2021·American Journal of Medical Genetics. Part a·Shira Litz PhilipsbornEyal Reinstein
Jun 13, 2021·Nature Communications·Saioa LópezGarrett Hellenthal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.