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Mitochondrial Kv1.3: a New Target in Cancer Biology?

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology

Dec 20, 2019

Vanessa ChecchettoLuigi Leanza

Abstract

Kv1.3 is a voltage gated potassium channel located in the plasma membrane, as well as at intracellular levels, such as mitochondria (mitoKv1.3), nucleus and Golgi apparatus. The plasma membrane channel has been shown to be important for cell proliferation, while the mitochondrial counte...read more

Mentioned in this Paper

Mitochondria
Neoplasms
Disease Progression
Wnt beta-Catenin Signaling Pathway
Plasma Membrane
Voltage-Gated Potassium Channel
CYP2C19*3 Allele
Malignant Neoplasms
Regulation of Biological Process
Orthotopic
Paper Details
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Mitochondrial Kv1.3: a New Target in Cancer Biology?

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology

Dec 20, 2019

Vanessa ChecchettoLuigi Leanza

PMID: 31854954

DOI: 10.33594/000000195

Abstract

Kv1.3 is a voltage gated potassium channel located in the plasma membrane, as well as at intracellular levels, such as mitochondria (mitoKv1.3), nucleus and Golgi apparatus. The plasma membrane channel has been shown to be important for cell proliferation, while the mitochondrial counte...read more

Mentioned in this Paper

Mitochondria
Neoplasms
Disease Progression
Wnt beta-Catenin Signaling Pathway
Plasma Membrane
Voltage-Gated Potassium Channel
CYP2C19*3 Allele
Malignant Neoplasms
Regulation of Biological Process
Orthotopic

Similar Papers Found In These Feeds

ROS Signalling in Cancer

Reactive oxygen species (ROS) have been found to be present in many cancers, having both pro-tumor promoting effects and anti-tumor signalling effects. The balance between the levels of ROS and tumorigenesis is still unclear. Discover the latest research on ROS signalling in cancer here.

Mammalian Cell Cycle & Cell Growth Control

Mammalian cell cycle is a complex process regulated by several signal transduction pathways and enzymes. Here is the latest research on regulation of mammalian cell cycle and growth.

Related Papers

Cell Calcium

Targeting a mitochondrial potassium channel to fight cancer

Cell CalciumDecember 3, 2014
Luigi LeanzaKatrin Anne Becker
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