Mitogen activated protein kinases (MAPKs) as regulators of spermatogenesis and spermatozoa functions

Molecular and Cellular Endocrinology
Tal Almog, Zvi Naor

Abstract

Spermatogenesis, culminating in the generation of mature motile spermatozoa, is a complex biological process that is regulated by cytokines and hormones of the male reproductive system. Spermatozoa must first undergo a series of biochemical processes termed capacitation, which is followed by acrosome reaction and egg fertilization. Here we review the role of mitogen-activated protein kinases (MAPK) cascades in spermatogenesis and spermatozoa functions.

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