PMID: 9186441Jun 1, 1997Paper

Mitomycin C-augmented trabeculectomy in refractory congenital glaucoma

Ophthalmology
A K MandalA Jayagandan

Abstract

The purpose of the study is to determine the safety and efficacy of mitomycin C-augmented trabeculectomy in children with developmental glaucoma treated previously by conventional procedures. Retrospective review of all cases of developmental glaucoma with previously failed conventional procedures that underwent mitomycin C-augmented trabeculectomy between January 1992 and December 1994. A total of 19 eyes of 13 patients were included in the study. Nineteen eyes included primary congenital glaucoma (15 eyes) with documented failure of primary trabeculotomy, Axenfeld-Reiger syndrome (2 eyes) and aniridia (2 eyes). Mitomycin C-augmented (0.4 mg/ml for 3 minutes) trabeculectomy was the chosen intervention. Preoperative and postoperative intraocular pressures (IOPs), visual acuities, success rate, bleb characteristics, time of surgical failure, and complications were the main outcome measures. The mean IOP was reduced from a preoperative level of 33.74 +/- 10.70 mmHg to 11.89 +/- 1.33 mmHg (P < 0.0001) with the percentage reduction in IOP being 64.75. The mean follow-up was 19.52 +/- 2.65 months. Visual acuity was maintained in all the cases after surgery. Complete success as defined in the authors' study was achieved in 18 eyes (9...Continue Reading

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Citations

Nov 20, 1998·American Journal of Ophthalmology·A D BeckR Noe
Oct 3, 2003·Ophthalmology·Anil K MandalTarannum Mansoori
Jan 25, 2005·The British Journal of Ophthalmology·R EhrlichD D Gaton
Mar 19, 2005·The British Journal of Ophthalmology·A Al-HazmiA Al-Mohammed
Feb 21, 2006·The British Journal of Ophthalmology·K A van OverdamP W T de Waard
Jul 9, 1999·The British Journal of Ophthalmology·A Azuara-BlancoJ J Augsburger
Jun 12, 1999·The British Journal of Ophthalmology·T S DietleinG K Krieglstein
May 29, 2003·The British Journal of Ophthalmology·R HillA Malayan
Jun 14, 2014·Eye·M PapadopoulosP T Khaw
Mar 23, 2006·Current Opinion in Ophthalmology·Suzana A Tanimoto, James D Brandt
Feb 18, 2016·Asia-Pacific Journal of Ophthalmology·Yar-Li TanChing-Lin Ho
Jun 1, 2014·Journal of Pediatric Ophthalmology and Strabismus·Sharaf KhanNeelakshi Bhagat
Jul 18, 2012·Journal of Pediatric Ophthalmology and Strabismus·Scott D Lawrence, Peter A Netland
Dec 18, 2007·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Sancy LowKen K Nischal
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Dec 8, 2004·Ophthalmology·Donald L BudenzEric Larson
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