Mitophagy in yeast: actors and physiological roles

FEMS Yeast Research
Ingrid Bhatia-Kissová, Nadine Camougrand

Abstract

Mitochondria are essential for oxidative energy production in aerobic eukaryotic cells, where they are also required for multiple biosynthetic pathways to take place. Mitochondria also monitor and evaluate complex information from the environment and intracellular milieu, including the presence or absence of growth factors, oxygen, reactive oxygen species, and DNA damage. It follows that disturbances of the integrity of mitochondrial function lead to the disruption of cell function, expressed as disease, aging, or cell death. It has been assumed that the degradation of damaged mitochondria by an autophagy-related pathway specific to mitochondria (mitophagy), recently found to be strictly regulated, is a fundamental process essential for cell homeostasis. Until now, the main role of mitophagy has been tentatively defined as a 'house-cleaning' pathway that allows to eliminate altered mitochondria, but mitophagy may also play a role in the adaptation of the number and quality of mitochondria to new environmental conditions. In yeast, recent data defined two categories of mitophagy actors: ones constitutively required for mitophagy and those with mitophagy-regulatory functions. Situations were also uncovered in normal physiology in...Continue Reading

References

Jan 1, 1982·Cell and Tissue Research·M J Heynen, R L Verwilghen
Apr 29, 1998·The Journal of Biological Chemistry·J G PastorinoJ L Farber
Jan 23, 1999·BioFactors·P BernardiL Scorrano
Jan 5, 2000·Genes & Development·M E CardenasJ Heitman
Apr 20, 2001·The Journal of Cell Biology·J KimD J Klionsky
Aug 21, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·S P ElmoreJ J Lemasters
Jan 17, 2003·Molecular Biology of the Cell·Paul RobertsDavid S Goldfarb
Aug 14, 2003·FEBS Letters·Jan A K W KielMarten Veenhuis
May 25, 1957·The Journal of Biophysical and Biochemical Cytology·S L CLARK
Jan 1, 1962·The Journal of Cell Biology·T P ASHFORD, K R PORTER
Jul 13, 2004·The Journal of Biological Chemistry·Ingrid KissováNadine Camougrand
Dec 29, 2004·Mechanisms of Ageing and Development·S Michal Jazwinski
Jun 11, 2005·Cell Death and Differentiation·M PriaultJ-C Martinou
Sep 24, 2005·Cell·Sophie PattingreBeth Levine
Oct 19, 2005·The Journal of Biological Chemistry·Usha Nair, Daniel J Klionsky
Oct 26, 2005·Cell Death and Differentiation·M Kundu, C B Thompson
Feb 25, 2006·Mechanisms of Ageing and Development·Byung Pal Yu, Hae Young Chung
Mar 21, 2006·Proceedings of the National Academy of Sciences of the United States of America·Li YuMichael Lenardo
May 9, 2006·Antioxidants & Redox Signaling·Alberto SanzGustavo Barja
Sep 16, 2006·Molecular Aspects of Medicine·Alexei TermanUlf T Brunk
Dec 6, 2006·Free Radical Biology & Medicine·Ingrid KissováNadine Camougrand
Mar 23, 2007·Autophagy·Ingrid KissováNadine Camougrand
May 4, 2007·Archives of Biochemistry and Biophysics·Insil KimJohn J Lemasters
Dec 1, 2007·Proceedings of the National Academy of Sciences of the United States of America·Rachel L SchweersPaul A Ney
Jan 9, 2008·The Journal of Biological Chemistry·Uta GeyUdo Krause-Buchholz
Sep 27, 2008·The Journal of Biological Chemistry·Tomotake Kanki, Daniel J Klionsky
Nov 26, 2008·The Journal of Cell Biology·Derek NarendraRichard J Youle
Dec 31, 2008·Autophagy·Angeles Rodríguez-HernándezJosé A Sánchez-Alcázar
Feb 3, 2009·Methods in Enzymology·Nadine CamougrandRodney J Devenish

❮ Previous
Next ❯

Citations

Nov 9, 2010·FEMS Yeast Research·Monique Bolotin-FukuharaClaude Gaillardin
Aug 29, 2012·Oxidative Medicine and Cellular Longevity·M Isabel González Siso, M Esperanza Cerdán
Jul 27, 2011·Journal of Visualized Experiments : JoVE·Dalibor MijaljicaRodney J Devenish
Aug 21, 2013·Oxidative Medicine and Cellular Longevity·Dmitry A KnorreFedor F Severin
Jul 30, 2014·Proceedings of the National Academy of Sciences of the United States of America·Mohamed Anwar Bin-UmerNilgun E Tumer
Mar 15, 2015·International Journal of Molecular Sciences·Adam BeachVladimir I Titorenko
Jan 20, 2016·Current Genetics·Isabella Sarto-Jackson, Lubomir Tomaska
Jul 3, 2013·IUBMB Life·Anna Leonov, Vladimir I Titorenko
Jan 4, 2012·Cellular Microbiology·Debasish GhoshAnthony P Sinai
Oct 4, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Benli WangXiaodong Liu
Sep 28, 2013·Essays in Biochemistry·Thomas MacVicar
Mar 6, 2012·Plant Physiology and Biochemistry : PPB·Farida MinibayevaVictoria Ryabovol
Aug 23, 2011·Molecular Cell·Joung Hyuck JooMondira Kundu
Jul 18, 2012·The International Journal of Biochemistry & Cell Biology·Ingrid Bhatia-Kiššová, Nadine Camougrand
Jul 26, 2011·Mitochondrion·Carlo M T MarobbioLuigi Palmieri
Aug 3, 2011·Biochimica Et Biophysica Acta·Catherine Dargemont, Batool Ossareh-Nazari
Aug 25, 2012·Biochimica Et Biophysica Acta·Magdalena FrankAndreas S Reichert
Jan 1, 2014·FEMS Yeast Research·Michael BreitenbachMarkus Ralser
Aug 29, 2020·Journal of Cachexia, Sarcopenia and Muscle·Sanaz MehrabaniAmirhossein Sahebkar
Oct 13, 2016·The Biochemical Journal·Ignacio AmigoAlicia J Kowaltowski
Mar 16, 2017·Frontiers in Immunology·Christian W Keller, Jan D Lünemann
Mar 27, 2020·International Journal of Molecular Sciences·Szymon StefaniakSławomir Borek
Jun 29, 2021·Frontiers in Cell and Developmental Biology·Jili ZhangJiyu Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autophagy & Model Organisms

Autophagy is a cellular process that allows degradation by the lysosome of cytoplasmic components such as proteins or organelles. Here is the latest research on autophagy & model organisms