PMID: 1090631Feb 1, 1975Paper

Mitosis in the cellular slime mold Polysphondylium violaceum

The Journal of Cell Biology
U P Roos


Myxamebas of Polysphondylium violaceum were grown in liquid medium and processed for electron microscopy. Mitosis is characterized by a persistent nuclear envelope, ring-shaped extranuclear spindle pole bodies (SPBs), a central spindle spatially separated from the chromosomal microtubules, well-differentiated kinetochores, and dispersion of the nucleoli. SPBs originate from the division, during prophase, of an electron-opaque body associated with the interphase nucleus. The nuclear nevelope becomes fenestrated in their vicinity, allowing the build-up of the intranuclear, central spindle and chromosomal microtubules as the SPBs migrate to opposite poles. At metaphase the chromosomes are in amphitelic orientation, each sister chromatid being directly connected to the corresponding SPB by a single microtubule. During ana- and telophase the central spindle elongates, the daughter chromosomes approach the SPBs, and the nucleus constricts in the equatorial region. The cytoplasm cleaves by furrowing in late telophase, which is in other respects characterized by a re-establishment of the interphase condition. Spindle elongation and poleward movement of chromosomes are discussed in relation to hypotheses of the mechanism of mitosis.


Mar 1, 1974·The Journal of Cell Biology·H Ris, D F Kubai
Jan 1, 1971·Annual Review of Microbiology·J T Bonner
Mar 26, 1973·Archiv für Mikrobiologie·W W Franke, P Reau
Nov 1, 1972·The Journal of Cell Biology·J R Aist, P H Williams
Jan 1, 1974·The Journal of Cell Biology·I B Heath
Aug 1, 1971·The Journal of Cell Biology·P B Moens, E Rapport
Jul 25, 1958·The Journal of Biophysical and Biochemical Cytology·M L WATSON
Jan 1, 1962·The Journal of Cell Biology·L E ROTH, E W DANIELS
Apr 1, 1960·The Journal of Biophysical and Biochemical Cytology·E H Mercer, B M Shaffer
May 1, 1971·The Journal of Cell Biology·J R McIntosh, S C Landis


Nov 20, 2012·Cellular and Molecular Life Sciences : CMLS·Irina TikhonenkoM P Koonce
Sep 1, 1985·The Journal of Cell Biology·T J Mitchison, M W Kirschner
Sep 1, 1985·The Journal of Cell Biology·T J Mitchison, M W Kirschner
Jan 1, 1976·The Journal of Cell Biology·P B Moens
Jun 1, 1977·The Journal of Cell Biology·D H Tippit, J D Pickett-Heaps
Dec 1, 1978·The Journal of Cell Biology·D H TippitJ D Pickett-Heaps
Aug 1, 1983·Biological Reviews of the Cambridge Philosophical Society·S P Szabo, Danton H O'Day
Mar 13, 2014·Biological Reviews of the Cambridge Philosophical Society·Danton H O'Day, Aldona Budniak

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