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Mitotic Gene Conversion Tracts Associated with Repair of a Defined Double-Strand Break in Saccharomyces cerevisiae

Genetics

Jul 27, 2017

Yee Fang Hum, Sue Jinks-Robertson

Abstract

Mitotic recombination between homologous chromosomes leads to the uncovering of recessive alleles through loss of heterozygosity. In the current study, a defined double-strand break was used to initiate reciprocal loss of heterozygosity between diverged homologs of chromosome IV in Sacc...read more

Mentioned in this Paper

M Phase, Mitotic
DNA Breaks, Double-Stranded
Biochemical Pathway
Repair - Remedial Action
Mitotic Gene Conversion
Research Activities
MLH1 protein, human
MLH1
Polaron
RNA Strand-exchange Activity
2
15
Paper Details
References
  • References22
  • Citations2
123

Mitotic Gene Conversion Tracts Associated with Repair of a Defined Double-Strand Break in Saccharomyces cerevisiae

Genetics

Jul 27, 2017

Yee Fang Hum, Sue Jinks-Robertson

PMID: 28743762

DOI: 10.1534/genetics.117.300057

Abstract

Mitotic recombination between homologous chromosomes leads to the uncovering of recessive alleles through loss of heterozygosity. In the current study, a defined double-strand break was used to initiate reciprocal loss of heterozygosity between diverged homologs of chromosome IV in Sacc...read more

Mentioned in this Paper

M Phase, Mitotic
DNA Breaks, Double-Stranded
Biochemical Pathway
Repair - Remedial Action
Mitotic Gene Conversion
Research Activities
MLH1 protein, human
MLH1
Polaron
RNA Strand-exchange Activity
2
15

Related Papers

Paper Details
References
  • References22
  • Citations2
123
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