PMID: 7032476Jan 1, 1981Paper

Mitotic regimen of different histological variants of lymphosarcoma

Arkhiv patologii
I A Kazantseva, N A Probatova

Abstract

Mitotic regimen of lymphosarcoma (75 observations), angiofollicular hyperplasia (5) and reactive hyperplasia of lymph nodes of the follicular type (34 observations--a group for comparison) was studied. The mitotic regimen values of non-Hodgkin's malignant lymphomas were found to vary in accordance with the morphological variant of the tumor. A higher mitotic activity in combination with high frequency and diversity of forms of mitosis pathology was typical of lymphoblast and immunoblast lymphosarcomas only. Prolymphocytic lymphosarcomas showed a relatively low mitotic activity. Lymphosarcoma with nodular growth showed a considerable decrease in mitotic activity as compared with nodular reactive hyperplasia. The emergence of multipolar mitoses is a reliable diagnostic sign of nodular lymphosarcoma.

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