PMID: 15218811Jun 29, 2004Paper

Mitoxantrone as a potential therapy for primary progressive multiple sclerosis

Multiple Sclerosis : Clinical and Laboratory Research
Olaf StüveScott S Zamvil

Abstract

Mitoxantrone (Novantrone) was the first drug approved in western Europe and North America for treatment of secondary progressive multiple sclerosis (SPMS) and progressive relapsing MS (PRMS). Pharmacological properties of mitoxantrone, its role in SPMS, the study rational and design of an ongoing multi-centre, double blind, randomized, placebo-controlled phase 2 trial will be outlined in this article.

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Citations

Dec 26, 2012·Journal of Photochemistry and Photobiology. B, Biology·Shweta AgarwalRanjana Mehrotra
Apr 29, 2006·Journal of Neuroimmunology·Clara M PelfreyRobert J Fox
Aug 13, 2005·Pharmacology & Therapeutics·Oliver NeuhausHans-Peter Hartung
Mar 6, 2010·Multiple Sclerosis : Clinical and Laboratory Research·Z KhaleeliA J Thompson
Oct 1, 2010·Continuum : Lifelong Learning in Neurology·Kathleen Hawker
May 14, 2005·Current Opinion in Neurology·Joep Killestein, Chris H Polman
Sep 12, 2018·Journal of Neurology·Rami FakihJames M Stankiewicz

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