Mitral bioprosthetic valve stenosis in a patient with antiphospholipid antibody syndrome and systemic lupus erythematosus.

General Thoracic and Cardiovascular Surgery
Akimasa MorisakiShigefumi Suehiro

Abstract

A 45-year-old woman with antiphospholipid antibody syndrome (APS) and systemic lupus erythematosus was admitted because of severe dyspnea. She had undergone mitral valve replacement (MVR) using a Mosaic bioprosthesis for infective endocarditis 9 years previously. She developed congestive heart failure secondary to mitral bioprosthetic valve stenosis resulting from relatively early structural valve deterioration. She underwent a second MVR using a mechanical valve prosthesis. The explanted bioprosthesis showed marked pannus formation and mineralization with fibrin thrombus formation, especially on the outflow surfaces of the leaflets. After the second operation, she was discharged without APS-related thromboembolic events under meticulous anticoagulant and antiplatelet therapies.

References

Jan 26, 2002·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Y KatoH Arimoto
Aug 9, 2002·The Journal of Thoracic and Cardiovascular Surgery·Walter Benno EichingerNiels Bleese
Oct 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Georg NollertBruno Reichart
Oct 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Robert Saeid Farivar, Lawrence H Cohn
Feb 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Yackov BerkunYaakov Naparstek
Mar 27, 2007·The Annals of Thoracic Surgery·Friedrich-Christian RiessNiels Bleese
Dec 18, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Hagen GorkiRex D L Stanbridge
Aug 22, 2009·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Friedrich-Christian RiessPeter Kremer
Aug 25, 2009·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Andrea ColliRicard Cervera
Sep 9, 2010·Lancet·Guillermo Ruiz-IrastorzaMunther A Khamashta

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Citations

Nov 18, 2014·TheScientificWorldJournal·Mahnoosh ForoughiMahmood Beheshti

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Related Concepts

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Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

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