Mitral clip - looking back and moving forward

Current Opinion in Cardiology
Neil P FamSubodh Verma

Abstract

Guidelines indicate surgical intervention for patients with symptomatic severe mitral regurgitation or signs of left ventricular dilatation or dysfunction. However, many patients do not receive surgery because of age or comorbidities, and have poor outcomes with conservative therapy. Transcatheter mitral repair with MitraClip (Abbott Vascular, IL, USA) has recently emerged as a viable treatment option for high-risk patients with heart failure. This article will review current evidence supporting the use of MitraClip across the spectrum of patient risk and discuss future directions for this technology. Both randomized and registry studies have demonstrated the efficacy and safety of MitraClip for mitral regurgitation reduction, with significant improvements in functional class and reductions in heart failure hospitalizations. With increasing global experience, a broader scope of patients and diseases can now be successfully treated, ranging from patients with failed surgical annuloplasty rings to those in cardiogenic shock. Ongoing randomized trials will further define the role of MitraClip in the management of heart failure patients with secondary mitral regurgitation. MitraClip is a useful therapeutic tool for nonsurgical pati...Continue Reading

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