PMID: 6978799May 1, 1982Paper

Mitral regurgitation in coronary artery disease

Chest
V BaluD C Dean

Abstract

Over a period of 5.25 years, 1,530 patients with coronary artery disease (CAD) underwent catheterization; 104 had associated mitral regurgitation (MR), and 60 had no complications. Twelve patients underwent coronary artery bypass graft surgery (CABG), with both pre- and postoperative angiograms. Nine of the 12 patients (75 percent) were in functional class 3 or 4. Left ventricular ejection fraction ranged from 34 to 75. The MR was considered severe (3+) in three, moderate (2+) in six, and trivial (1+) in three patients. Following CABG, all except two patients were in class 1. Of the 43 patients medically treated, 31 patients (72 percent) were in functional class 3 or 4. Angiographic results showed that five patients had 3+ MR, 14 had 2+ MR, and 24 had 1+ MR. The EF was less than 30 in 23 patients and greater than or equal to 30 in 20 patients, and left ventricular filling pressure was elevated. Twenty patients died, with a mean follow-up period of 11 months. Our study demonstrates that the surgically treated patients showed angiographic improvement in MR, improved functional status, and relief of symptoms compared with medically treated patients. We believe that a subset of patients with MR and CAD would benefit with CABG.

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Citations

Oct 8, 2003·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Atsushi YamaguchiTakashi Ino
Sep 11, 2013·Current Treatment Options in Cardiovascular Medicine·Robert Michler
Mar 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Hari R MallidiStephen E Fremes
Jun 25, 2014·Current Cardiology Reports·Mina M BenjaminPaul A Grayburn
Oct 22, 2008·Scandinavian Cardiovascular Journal : SCJ·Per WierupHenning Mølgaard
Oct 14, 2008·Scandinavian Cardiovascular Journal : SCJ·Per WierupUNKNOWN MoMIC Trial Investigators
Jul 31, 2007·Journal of Cardiac Surgery·Shahzad G Raja, Geoffrey A Berg
Jul 26, 2005·The Annals of Thoracic Surgery·Daniel R WongDavid F Torchiana
Oct 1, 1986·The American Journal of Cardiology·F LoperfidoU Manzoli
Jul 27, 2006·Asian Cardiovascular & Thoracic Annals·Khalid A OsmanMohamed H Ahmed
May 4, 2012·Circulation·Michael H KwonFrederick Y Chen
Jan 1, 1985·Acta Medica Scandinavica·B O OlofssonK A Jacobsson
May 24, 2020·Journal of Alzheimer's Disease : JAD·Jack C de la Torre
May 1, 2021·Biomedicines·Mattia VinciguerraErnesto Greco

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