Abstract
We evaluated 32 young patients with mitral valve prolapse (MVP) as the only recognized cause of cerebral ischemia. The mean follow-up from the time of the first ischemic event was 8 years. At the time of the follow-up evaluation, 24 patients (75%) had a normal cardiac examination, and 4 had midsystolic clicks; only 1 had the characteristic click-murmur. In 75%, the first ischemic event was stroke. When MVP-associated ischemia was recognized, 44% had recurrent ischemic events. In the mean 4-year period between diagnosis of MVP-associated ischemia and follow-up, 16% had recurrent ischemic events, but none had a new persistent deficit from these events. At the time of follow-up, 63% of patients were taking platelet antiaggregants or anticoagulants. These data suggest a good prognosis for recurrent ischemic events after diagnosis of MVP-associated ischemia.
Citations
Dec 1, 1986·Journal of the American College of Cardiology·J H ChesebroV Fuster
Jul 10, 2003·Lancet Neurology·José M Ferro
Aug 15, 2003·Southern Medical Journal·Roger E Kelley, Alireza Minagar
Oct 15, 2005·The International Journal of Neuroscience·Başak KarakurumSibel Benli
Sep 24, 2004·Chest·Deeb N SalemStephen G Pauker
May 19, 2006·Mayo Clinic Proceedings·Harold P Adams
Feb 1, 1989·Chest·D G ShermanR G Hart
May 1, 1987·American Heart Journal·P A Wolf, C A Sila
Jul 1, 1985·Survey of Ophthalmology·J W GittingerR M Burde
Jul 1, 1988·Current Problems in Cardiology·W J PennyV Fuster
Oct 1, 1989·American Heart Journal·H BoudoulasC F Wooley
Jun 1, 1987·The Physician and Sportsmedicine·R C McFaul
Jul 24, 2008·Chest·Deeb N SalemStephen G Pauker
Jan 1, 1995·Stroke; a Journal of Cerebral Circulation·A J OrenciaJ P Whisnant
Mar 1, 1985·Stroke; a Journal of Cerebral Circulation·D R Boughner, H J Barnett
Mar 1, 1985·Stroke; a Journal of Cerebral Circulation·R G Hart, D G Sherman
May 1, 1991·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·A Shuaib, W F Murphy
Apr 1, 1992·Acta Ophthalmologica·Z ButtH McLean
Nov 15, 1988·Klinische Wochenschrift·C BaumgartnerB R Binder
Feb 1, 1986·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·A C Jackson
Sep 1, 1987·Postgraduate Medicine·D C Anderson
Sep 1, 1994·Arquivos de neuro-psiquiatria·A Leboreiro-FernandezM V Moura-Ribeiro