Mitral valve repair with minimally invasive approaches vs sternotomy: A meta-analysis of early and late results in randomized and matched observational studies

Journal of Cardiac Surgery
Michel Pompeu B O SáGilles Dreyfus

Abstract

Minimally invasive cardiac surgery (MICS) for mitral valve repair (MVRp) has been increasingly used. This study aimed to evaluate the early and late results of MICS for MVRp vs conventional sternotomy. A systematic review of randomized controlled trials or observational studies (with matched populations) comparing MICS and conventional MVRp reporting any of the following outcomes: mortality, MVRp failure, complications, blood transfusion, readmission within 30 days after discharge, long-term reoperation for mitral regurgitation, operative times, mechanical ventilation time, intensive care unit (ICU) stay, or hospital stay. The pooled treatment effects were calculated using a random-effects model. Ten studies involving 6792 patients (MICS: 3396 patients; Conventional: 3296 patients) met the eligibility criteria. In the pooled analysis, MICS significantly reduced the risk for blood transfusion (odds ratio [OR], 0.654; 95% confidence interval [CI] 0.462-0.928; P = .017) and readmission within 30 days after discharge (OR, 0.615; 95% 0.456-0.829; P = .001). MICS was associated with a significantly longer cross-clamp time (mean difference 14 minutes; 95% CI, 7.4-21 minutes; P < .001), CPB time (24 minutes; 95% CI, 14-35 minutes; P < ...Continue Reading

References

Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Apr 21, 2005·BMC Medical Research Methodology·Stela Pudar HozoIztok Hozo
Jun 30, 2006·Contemporary Clinical Trials·Rebecca DerSimonian, Raghu Kacker
Sep 18, 2007·Seminars in Thoracic and Cardiovascular Surgery·Farzan Filsoufi, Alain Carpentier
Apr 1, 2008·The Journal of Thoracic and Cardiovascular Surgery·A Marc GillinovLars G Svensson
Oct 3, 2008·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Paul ModiWalter Randolph Chitwood
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Dec 1, 2009·The Journal of Thoracic and Cardiovascular Surgery·Lars G SvenssonBruce W Lytle
Jul 9, 2010·The Annals of Thoracic Surgery·William T BrinkmanWilliam H Ryan
Mar 23, 2012·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Davy C H ChengVolkmar Falk
Sep 23, 2014·The Journal of Thoracic and Cardiovascular Surgery·Eugene A GrossiUNKNOWN Economic Workgroup on Valvular Surgery
Feb 3, 2015·Trends in Cardiovascular Medicine·Khaled D AlgarniHartzell Schaff
Sep 14, 2016·The Annals of Thoracic Surgery·Rüdiger LangeThomas Günther
Oct 14, 2016·BMJ : British Medical Journal·Jonathan Ac SterneJulian Pt Higgins
Apr 14, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Michele De BonisOttavio Alfieri
Sep 10, 2017·European Heart Journal·Helmut BaumgartnerUNKNOWN ESC Scientific Document Group
Nov 13, 2017·Progress in Cardiovascular Diseases·Mateo Marin CuartasMichael A Borger
Jan 6, 2018·Interactive Cardiovascular and Thoracic Surgery·Qing WangZhinong Wang
Oct 23, 2018·The Journal of Thoracic and Cardiovascular Surgery·Gilles D DreyfusAdelin Albert
Aug 30, 2019·BMJ : British Medical Journal·Jonathan A C SterneJulian P T Higgins

❮ Previous
Next ❯

Citations

Jun 5, 2021·Seminars in Thoracic and Cardiovascular Surgery·Joseph Lamelas, Ahmed Alnajar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.