Mix-breeding with HEV-infected swine induced inapparent HEV infection in SPF rabbits

Journal of Medical Virology
Lin LiuHui Zhuang

Abstract

Studies have shown that swine HEV (sHEV) and rabbit HEV (rHEV) can experimentally infect rabbits and swine, respectively. However, no published data have documented isolating sHEV strains from rabbits in natural environment so far. To clarify the possibility of natural cross-species transmission of sHEV to rabbits, the pigs with HEV infection were farmed along with SPF rabbits in the same enclosed space. Five of 10 rabbits had seroconversion for anti-HEV antibody from the third week after mix-breeding. However, HEV RNA remained undetectable in feces, serum, liver and bile of the ten rabbits; and no obvious elevation of ALT was observed. The results possibly suggested that sHEV might lead to an inapparent infection of SPF rabbits by fecal-oral route.

References

Sep 2, 1997·Proceedings of the National Academy of Sciences of the United States of America·X J MengS U Emerson
May 31, 2001·Journal of Viral Hepatitis·V A ArankalleV S Padbidri
Jun 15, 2001·ILAR Journal·R H Purcell, S U Emerson
Jul 13, 2002·Journal of Medical Virology·You-Chun WangTim J Harrison
Jul 10, 2003·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Akiko KunoHiroaki Okamoto
Aug 30, 2005·Journal of Virological Methods·Narayanan JothikumarVincent R Hill
Jan 18, 2006·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Masaji NakamuraShunji Mishiro
Feb 22, 2008·The New England Journal of Medicine·Nassim KamarLionel Rostaing
Jul 22, 2008·Zoonoses and Public Health·W ZhangX Hua
Nov 11, 2008·The Lancet Infectious Diseases·Harry R DaltonMalcolm Banks
Dec 3, 2008·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P ColsonR Gérolami
Jun 25, 2009·Journal of Medical Virology·Chenyan ZhaoYouchun Wang
Aug 14, 2009·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yibin ChangHui Zhuang
Dec 17, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C G Teo
Oct 15, 2011·Journal of Clinical Microbiology·Chen DongChong-Gee Teo
Nov 22, 2011·Emerging Infectious Diseases·Caitlin M CossaboomXiang-Jin Meng
Jul 31, 2012·Emerging Infectious Diseases·Jacques IzopetJean-Luc Guérin
Sep 28, 2012·The New England Journal of Medicine·Jay H HoofnagleRobert H Purcell
Nov 28, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Yansheng GengYouchun Wang
May 1, 2013·Emerging Infectious Diseases·Peng LiuHui Zhuang
Jan 7, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·J E ArendsD Salmon
Mar 29, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·James LaraYury E Khudyakov

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Citations

Jan 21, 2019·Transboundary and Emerging Diseases·Yansheng GengYouchun Wang

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