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Mixed anhydrides (phosphoric-carboxyl) are also formed in the esterification of 5'-AMP with N-acetylaminoacyl imidazolides: implications regarding the origin of protein synthesis

Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life

Jan 1, 1992

N S Wickramasinghe, J C Lacey

PMID: 11537548

Abstract

Procedures for the formation of aminoacyl esters of monoribonucleotides with aminoacyl imidazolides were first reported by Gottikh et al. and summarized in 1970. This reaction has been widely used by us and numbers of other workers as a convenient means of preparing aminoacyl esters of ...read more

Mentioned in this Paper

Anhydrides
Phosphate Measurement
Protein Biosynthesis
Nucleotides
Imidazoles
Phosphaden
Esters
Amino Acid [EPC]
Phosphate ion
Esterification
Paper Details
References
  • References15
  • Citations8
12
  • References15
  • Citations8

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M IllangasekareM Yarus
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Mixed anhydrides (phosphoric-carboxyl) are also formed in the esterification of 5'-AMP with N-acetylaminoacyl imidazolides: implications regarding the origin of protein synthesis

Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life

Jan 1, 1992

N S Wickramasinghe, J C Lacey

PMID: 11537548

DOI:

Abstract

Procedures for the formation of aminoacyl esters of monoribonucleotides with aminoacyl imidazolides were first reported by Gottikh et al. and summarized in 1970. This reaction has been widely used by us and numbers of other workers as a convenient means of preparing aminoacyl esters of ...read more

Mentioned in this Paper

Anhydrides
Phosphate Measurement
Protein Biosynthesis
Nucleotides
Imidazoles
Phosphaden
Esters
Amino Acid [EPC]
Phosphate ion
Esterification

Related Papers

Journal of Molecular Evolution

Chemical esterification of 5'-AMP occurs predominantly at the 2' position

Journal of Molecular EvolutionOctober 1, 1990
J C LaceyC L Watkins
Science

Aminoacyl-RNA synthesis catalyzed by an RNA

ScienceFebruary 3, 1995
M IllangasekareM Yarus
Paper Details
References
  • References15
  • Citations8
12
  • References15
  • Citations8
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