Abstract
Nontuberculous mycobacteria (NTMs) are ubiquitous and are being increasingly reported as human opportunistic infection. Cutaneous infection caused by mixed NTM is extremely rare. We encountered the case of a 46-year-old female, who presented with multiple discharging sinuses over the lower anterior abdominal wall (over a previous appendectomy scar) for the past 2 years. Microscopy and culture of the pus discharge were done to isolate and identify the etiological agent. Finally, GenoType Mycobacterium CM/AS assay proved it to be a mixed infection caused by Mycobacterium szulgai and M. intermedium. The patient was advised a combination of rifampicin 600 mg once daily, ethambutol 600 mg once daily, and clarithromycin 500 mg twice daily to be taken along with periodic follow-up based upon clinical response as well as microbiological response. We emphasize that infections by NTM must be considered in the etiology of nonhealing wounds or sinuses, especially at postsurgical sites.
References
Aug 1, 1991·Journal of Clinical Microbiology·S KusunokiE Yabuuchi
Dec 1, 1988·Applied and Environmental Microbiology·L A CarsonR C Good
Sep 1, 1981·Reviews of Infectious Diseases·A Timpe, E H Runyon
Apr 1, 1993·International Journal of Systematic Bacteriology·A MeierE C Böttger
May 1, 1995·Clinics in Dermatology·F Portaels
Apr 1, 1996·Clinical Microbiology Reviews·J O Falkinham
Jun 12, 1998·The European Respiratory Journal·E TortoliS Emler
Jan 19, 1999·Annual Review of Microbiology·R J WallaceD E Griffith
Mar 30, 2002·Journal of Clinical Microbiology·Qing ZhangJill E Clarridge
Apr 1, 2003·Bone Marrow Transplantation·P FriskG Lönnerholm
Oct 18, 2003·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Somnuek SungkanuparphRoongnapa Pracharktam
Nov 8, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M L Abalain-CollocB Picard
Dec 11, 2003·Respiration; International Review of Thoracic Diseases·José M F Sánchez-AlarcosJosé L Alvarez-Sala
Feb 4, 2006·Journal of Clinical Microbiology·Cristina RussoDonato Menichella
May 5, 2006·Journal of Clinical Microbiology·Elvira RichterDoris Hillemann
Jun 27, 2007·Maternal and Child Health Journal·Jill A McDonaldBrian Morrow
Jan 12, 2008·Chest·Jeffrey Glassroth
May 1, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jakko van IngenDick van Soolingen
Jun 9, 2009·Journal of Medical Microbiology·Andie S LeeGwendolyn L Gilbert
Nov 16, 2011·Clinical Medicine Insights. Case Reports·Hiromitsu OhtaToshihiro Nukiwa
Citations
Jan 14, 2017·Zoonoses and Public Health·S ThirunavukkarasuR J Whittington
Mar 28, 2017·International Journal of Dermatology·Jesus A Torres-CoyJacobus H de Waard
Jun 2, 2017·Cytokine·Richard T Robinson, Anna R Huppler
Feb 28, 2018·Journal of Bacteriology·Tiffany A Claeys, Richard T Robinson
Jun 24, 2016·The Open Microbiology Journal·Nyasha Chin'ombePasipanodya Nziramasanga
Aug 7, 2021·Pathogens·Visal KhieuKiatichai Faksri