Mixed medullary and follicular carcinoma of the thyroid

Virchows Archiv. A, Pathological Anatomy and Histopathology
M PfaltzJ P Mühlethaler

Abstract

We report a case of medullary carcinoma of the thyroid which on light microscopy showed not only the well known arrangement of cells in sheets and nests but also unequivocal follicular structures. These follicular structures are present both in the primary tumor and in lymph node metastases. Immunohistochemical investigations revealed that the cells lining the follicles produce thyroglobulin, whereas the remaining tumor tissue is positive for calcitonin and carcinoembrionic antigen. This case represents a medullary carcinoma of the thyroid with an atypical pattern consisting of both thyroglobulin and calcitonin producing cells.

References

Jan 1, 1978·The Journal of Surgical Research·P Lo GerfoC Feind
Nov 1, 1979·Cancer·G Bussolati, G Monga
Oct 1, 1971·Seminars in Nuclear Medicine·L B Woolner
Sep 1, 1973·Acta Endocrinologica·J G LjunggrenB Hjern
Jul 1, 1974·American Journal of Surgery·M S Didolkar, G E Moore
Nov 1, 1968·The American Journal of Medicine·H W WahnerF Aljure
Mar 1, 1966·Journal of Clinical Pathology·E D WilliamsI Doniach
May 1, 1967·Cancer·M L IbanezR L Clark
Jan 1, 1981·Neurobiology of Aging·I F RoubeinF S Ordway
Jan 1, 1959·The Journal of Clinical Endocrinology and Metabolism·J B HAZARDG CRILE

❮ Previous
Next ❯

Citations

Mar 1, 1991·Seminars in Surgical Oncology·A L WatneA Sohrabi
Jan 1, 1989·Virchows Archiv. A, Pathological Anatomy and Histopathology·R HolmJ V Johannessen
Jul 31, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·E KaiserW Worofka
May 1, 1995·Pathology, Research and Practice·G BussolatiA Pagani
Jan 1, 1991·Thyroid : Official Journal of the American Thyroid Association·M NoelM S Moukhtar
Dec 14, 2004·Thyroid : Official Journal of the American Thyroid Association·M-C VantyghemM Lecomte-Houcke
Feb 1, 1996·The American Journal of Surgical Pathology·G C PastoleroS L Asa
Apr 8, 2004·Clinical Nuclear Medicine·Parul BhatnagarRavi Kashyap
Jan 1, 1991·Cytopathology : Official Journal of the British Society for Clinical Cytology·M E MendonçaJ Soares
Sep 1, 1993·Histopathology·M Sobrinho-Simŏes
Jun 1, 1989·Acta Pathologica Japonica·N LertprasertsukeM Kubota
Nov 30, 2013·Case Reports in Endocrinology·Maasumeh TohidiIraj Nabipour
Jan 1, 1986·Ultrastructural Pathology·R HolmJ V Johannessen
Jan 1, 1985·Ultrastructural Pathology·M A Sobrinho-SimõesJ V Johannessen
May 1, 1995·Pathology, Research and Practice·E Fonseca, M Sobrinho-Simões
Mar 5, 2009·Head & Neck·Charlette NangueSnezana Andrejevic-Blant
Nov 1, 1989·The Journal of Pathology·F T Bosman
Aug 1, 1986·Histopathology·N W WilsonE Heyderman
Apr 30, 1998·The Journal of Veterinary Medical Science·M KuwamuraS Sakuma
Jan 9, 2019·Cell and Tissue Research·Yoko Kameda
May 1, 1990·The Journal of Pathology·N A Wright
Jun 1, 1990·Endocrine Pathology·Virginia A LiVoisi
Aug 1, 1995·Journal of Surgical Oncology·K KobayashiY Horie
Jun 5, 2021·Clinical Case Reports·Vanessa GuerreiroIsabel Torres

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.