Mixed Spectrum Analysis on fMRI Time-Series

IEEE Transactions on Medical Imaging
Arun KumarJagath C Rajapakse

Abstract

Temporal autocorrelation present in functional magnetic resonance image (fMRI) data poses challenges to its analysis. The existing approaches handling autocorrelation in fMRI time-series often presume a specific model of autocorrelation such as an auto-regressive model. The main limitation here is that the correlation structure of voxels is generally unknown and varies in different brain regions because of different levels of neurogenic noises and pulsatile effects. Enforcing a universal model on all brain regions leads to bias and loss of efficiency in the analysis. In this paper, we propose the mixed spectrum analysis of the voxel time-series to separate the discrete component corresponding to input stimuli and the continuous component carrying temporal autocorrelation. A mixed spectral analysis technique based on M-spectral estimator is proposed, which effectively removes autocorrelation effects from voxel time-series and identify significant peaks of the spectrum. As the proposed method does not assume any prior model for the autocorrelation effect in voxel time-series, varying correlation structure among the brain regions does not affect its performance. We have modified the standard M-spectral method for an application on...Continue Reading

References

Feb 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E BullmoreP Sham
Sep 1, 1995·NeuroImage·K J Worsley, K J Friston
Oct 27, 1998·Human Brain Mapping·R L Buckner
Apr 7, 1999·NeuroImage·M S DagliJ V Haxby
Oct 5, 2001·IEEE Transactions on Bio-medical Engineering·J C Rajapakse, J Piyaratna
Jan 5, 2002·NeuroImage·K J WorsleyA C Evans
Feb 18, 2004·IEEE Transactions on Medical Imaging·Mark W WoolrichStephen M Smith
Feb 28, 2004·Brain Research·Janusz FrackowiakBozena Mazur-Kolecka
Apr 22, 2005·Biostatistics·F Dubois Bowman
Aug 16, 2005·NeuroImage·Torben E LundThomas E Nichols
Jun 14, 2006·IEEE Transactions on Medical Imaging·Yang Wang, Jagath C Rajapakse
Jun 19, 2009·Magnetic Resonance Imaging·Shing-Chung NganPek-Lan Khong
Apr 7, 2010·Medical Image Analysis·Wanmei OuPolina Golland
Mar 29, 2011·Frontiers in Human Neuroscience·Martin M Monti

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Citations

Dec 29, 2020·Frontiers in Neuroscience·Xiuling LiuFeng Lin

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