Mixing enhancement in microfluidic channel with a constriction under periodic electro-osmotic flow.

Biomicrofluidics
Chun Yee LimChun Yang

Abstract

We present a new approach to enhance mixing in T-type micromixers by introducing a constriction in the microchannel under periodic electro-osmotic flow. Two sinusoidal ac electric fields with 180 degrees phase difference and similar dc bias are applied at the two inlets. The out of phase ac electric field induces oscillation of fluid interface at the junction of the two inlet channels and the constriction. Due to the constriction introduced at the junction, fluids from these two inlets form alternative plugs at the constricted channel. These plugs of fluids radiate downstream from the constriction into the large channel and form alternate thin crescent-shaped layers of fluids. These crescent-shaped layers of fluids increase tremendously the contact surface area between the two streams of fluid and thus enhance significantly the mixing efficiency. Experimental results and mixing mechanism analysis show that amplitude and frequency of the ac electric field and the length of the constriction govern the mixing efficiency.

References

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Citations

Jan 10, 2012·Analytical Chemistry·Vladimir GubalaDavid E Williams
Aug 22, 2012·Lab on a Chip·Yanrui JuZhihong Li
Jul 11, 2012·Lab on a Chip·Haiwang LiTeck Neng Wong
May 15, 2013·Lab on a Chip·Wenqi HuAaron T Ohta
Aug 7, 2010·Biomicrofluidics·Mranal Jain, K Nandakumar
Jun 20, 2012·Biomicrofluidics·Hendryk BockelmannDominik P J Barz
Aug 7, 2013·Biomicrofluidics·Ruey-Jen YangLung-Ming Fu
Mar 1, 2016·Scientific Reports·Chun Yee LimYee Cheong Lam
May 7, 2015·Biomicrofluidics·An Eng LimYee Cheong Lam
Jul 19, 2016·Analytical Chemistry·An Eng LimYee Cheong Lam
Jul 25, 2017·Analytical Chemistry·Chun Yee LimYee Cheong Lam
Jun 21, 2011·International Journal of Molecular Sciences·Chia-Yen LeeLung-Ming Fu
Oct 11, 2017·Advanced Healthcare Materials·Jalal MosayebiSophie Laurent
Nov 10, 2015·Journal of Micromechanics and Microengineering : Structures, Devices, and Systems·Kevin Ward, Z Hugh Fan
Nov 15, 2018·Micromachines·An Eng LimRafael Taboryski
Feb 16, 2019·Biomicrofluidics·Hua GongGregory P Nordin
Dec 29, 2019·Scientific Reports·Emir YasunIgor Mezić
Sep 28, 2010·Physical Review Letters·Sanjeeva Balasuriya
Dec 2, 2014·ACS Applied Materials & Interfaces·Chuanzhao ChenXinxin Li

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Methods Mentioned

BETA
chip

Software Mentioned

MATLAB

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