Mixtures of tritiated water, zinc and dissolved organic carbon: Assessing interactive bioaccumulation and genotoxic effects in marine mussels, Mytilus galloprovincialis

Journal of Environmental Radioactivity
Holly B C PearsonAwadhesh N Jha

Abstract

Release of tritium (3H) in the marine environment is of concern with respect to its potential bioaccumulation and detrimental impact on the biota. Previous studies have investigated the uptake and toxicity of this radionuclide in marine mussels, and the interaction of3H with dissolved organic ligands and elevated temperature. However, despite the well-established view that toxicity is partly governed by chemical speciation, and that toxic effects of mixture of contaminants are not always additive, there have been no studies linking the prevailing chemistry of exposure waters with observed biological effects and tissue specific accumulation of3H in combination with other constituents commonly found in natural waters. This study exposed the marine mussel Mytilus galloprovincialis for 14 days to mixtures of3H (as tritiated water, HTO) and zinc (Zn) at 5 Mbq L-1, and 383, 1913 and 3825 nM Zn, respectively, to investigate (a)3H and Zn partitioning in soft tissues of mussels, and (b) DNA damage in haemocytes, determined using the single cell gel electrophoresis or the comet assay. Additionally, the extent of association of3H with dissolved organic carbon (DOC, added as humic acid) over the exposure period was investigated in order to...Continue Reading

Citations

Sep 25, 2020·International Journal of Radiation Biology·Emily L VernonAwadhesh N Jha

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