MO-A-BRB-01: Non-Coplanar Rotational Therapy by Using High Efficient Unflattened Beams

Medical Physics
H ChenC Liu

Abstract

The rapid dose fall-off from treatment target to the adjacent critical organs has been the Holy Grail for radiotherapy treatment planning. The modern treatment delivery technologies to address such goal include volumetric modulated rotational therapy, non-coplanar EVIRT beams and the use of unflattened beams to reduce the penumbra area. In this lecture, the integration of above techniques will be presented to achieve the goal of a sharp gradient dose around the target and also the discussion of middle to low dose volumes. Use of volumetric modulated rotational therapy by multiple non-coplanar arcs is an idea treatment modality to focus the high dose in the target area while spreading the low dose to even larger volume to reduce the middle range dose to surrounding critical organs. This is especially important for SBRT treatment plans since the fraction dose is much higher than the traditional fraction schema. The challenges we face today are 1. the gantry-couch (patient) collision issue for non-coplanar beam angles, 2. the treatment delivery efficiency due to multiple arc rotations and 3. the massive inverse optimization computation for multiple rotational arcs can be resource intensive and time consuming for treatment plan sys...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.