MO-D-BRB-03: Comparison of Proton Therapy Institutional Data Collected by the RPC

Medical Physics
Paige A SummersDavid S Followill

Abstract

To detail and compare data collected during RPC onsite dosimetry review visits at proton therapy centers. The RPC has established a complete review process for proton therapy institutions wishing to participate in NCI-funded clinical trials that includes an on-site dosimetry review visit performed by the RPC. During the visit, the RPC takes measurements that include CT# vs. relative stopping power (RSP) conversion, beam output, depth dose, lateral profiles, QA procedure reviews and anthropomorphic phantom irradiations. The RPC reviewed beam output, depth dose and lateral profiles for 5 specific anatomic treatment sites, reference, prostate, lung, brain, and spine as compared to the institution's measured or treatment planning-derived values. In addition, the RPC has compared results from each institution's proton prostate phantom irradiation. All of the institutions visited had RPC/Institution output ratios that ranged between 0.95 - 1.02 where the acceptance criterion was ±5%. For the CT# to RSP comparison, there was a larger variability. Only two institutions agreed within five percent of the recommended values, while the other five institutions had disagreements of up to 20 percent in the high density (high CT number) region...Continue Reading

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