MO-F-BRB-04: Fast Estimation of Secondary Particle Therapy Dose Using a Modified Track Repeating Method

Medical Physics
R KeyesS Luan

Abstract

Charged particle beams are of great interest, because they can achieve highly conformal radiation dose distributions. Despite this, some scattered radiation is inevitably present outside of the target volumes, and is of concern because of risks such as radiogenic cancer. Accurately calculating the secondary dose in regions far from the target volume is very difficult due to extremely low particle fluence and the effect of heterogeneities on particle ranges, making calculations possible only with CPU-week long Monte Carlo runs. By using a modified track repeating method, we demonstrate fast and accurate estimation of secondary dose appropriate for clinical use. Primary and secondary particle track databases (including protons, electrons, photons, neutrons, and positrons) were generated with the Geant4 Monte Carlo toolkit. Several new strategies were developed or employed to improve the performance of non- primary particle propagation, including: (1) processing the databases such that only primary tracks producing deep penetrating photons or neutrons were kept and particles falling below transport thresholds were discarded, (2) a search algorithm that can locate a sub-track for a given energy in constant time, (3) multiplying pho...Continue Reading

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