PMID: 9426031Jan 13, 1998Paper

Mobile aortic atheroma and systemic emboli: efficacy of anticoagulation and influence of plaque morphology on recurrent stroke

Journal of the American College of Cardiology
F A DresslerA J Labovitz

Abstract

We sought to determine the influence of plaque morphology and warfarin anticoagulation on the risk of recurrent emboli in patients with mobile aortic atheroma. An epidemiologic link between aortic atheroma and systemic emboli has been described both in pathologic and transesophageal studies. Likewise, a few studies have found an increased incidence of recurrent emboli in these patients. The therapeutic implications of these findings has not been studied. Thirty-one patients presenting with a systemic embolic event and found to have mobile aortic atheroma were studied. The height, width and area of both immobile and mobile portions of atheroma were quantitated. The dimensions of the mobile component was used to define three groups: small, intermediate and large mobile atheroma. The patients were followed up by means of telephone interview and clinical records, with emphasis on anticoagulant use and recurrent embolic or vascular events. Patients not receiving warfarin had a higher incidence of vascular events (45% vs. 5%, p = 0.006). Stroke occurred in 27% of these patients and in none of those treated with warfarin. The annual incidence of stroke in patients not taking warfarin was 0.32. Myocardial infarction occurred in 18% of ...Continue Reading

References

Jan 1, 1978·The American Journal of the Medical Sciences·F J BrunsS Adler
Dec 1, 1992·Annals of Internal Medicine·F A DeRookR L Popp
Aug 1, 1992·Stroke; a Journal of Cerebral Circulation·K ToyodaT Yamaguchi
Jan 23, 1992·The New England Journal of Medicine·P AmarencoJ J Hauw
Sep 15, 1991·Annals of Internal Medicine·P A TunickI Kronzon
Sep 1, 1991·Annals of Vascular Surgery·L H HollierC D Procter
Jan 11, 1991·Journal of the American College of Cardiology·D G KaralisG S Mintz
Mar 1, 1991·Annals of Internal Medicine·P A TunickI Kronzon
Dec 1, 1994·The New England Journal of Medicine·P AmarencoM G Bousser
Apr 1, 1994·Journal of the American College of Cardiology·P A TunickI Kronzon
Jan 1, 1994·Stroke; a Journal of Cerebral Circulation·G W AlbersJ Hotson
Feb 1, 1994·American Heart Journal·M NishinoT Kamada
May 15, 1993·The American Journal of Cardiology·P NihoyannopoulosC M Oakley
Mar 1, 1996·Journal of the American College of Cardiology·M KhatibzadehA Sheikhzadeh
May 9, 1996·The New England Journal of Medicine·UNKNOWN French Study of Aortic Plaques in Stroke GroupM-G Bousser
Nov 7, 1996·The New England Journal of Medicine·M R Di TullioS Homma
Sep 5, 1957·The New England Journal of Medicine·W M THURLBECK, B CASTLEMAN
Dec 1, 1961·Annals of Internal Medicine·W FEDER, R AUERBACH

❮ Previous
Next ❯

Citations

Jun 25, 2005·Current Atherosclerosis Reports·Timothy D Woods
Jun 5, 2003·Current Treatment Options in Cardiovascular Medicine·Geoffrey A. DonnanPierre Amarenco
May 9, 2007·Current Treatment Options in Cardiovascular Medicine·Theresa A MolisseItzhak Kronzon
Sep 16, 2010·Current Treatment Options in Cardiovascular Medicine·Carlos G Santos-GallegoJuan José Badimón
Nov 30, 2000·Current Treatment Options in Neurology·K Vahedi, P Amarenco
Jun 11, 1999·International Journal of Cardiology·A SheikhzadehU Stierle
Jul 24, 2003·Journal of the American College of Cardiology·Yoshihiro FukumotoUNKNOWN Cholesterol Embolism Study(CHEST) Investigators
Sep 19, 2003·Journal of the American College of Cardiology·Ramon Castello, Thomas G Brott
Apr 8, 1999·Journal of the American College of Cardiology·E FerrariM Baudouy
Apr 8, 1999·Journal of the American College of Cardiology·V G Dávila-RománB Barzilai
Mar 15, 2000·Journal of the American College of Cardiology·P A Tunick, I Kronzon
Jul 10, 2003·Lancet Neurology·José M Ferro
Jan 19, 2013·Molecular Pharmaceutics·Katie L CiesienskiPeter Caravan
May 2, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yuka TerasawaNoriko Matsumoto
Apr 11, 2003·The New England Journal of Medicine·Mary E Charlson, O Wayne Isom
Mar 17, 2012·European Heart Journal·Bernhard MeierHans C Diener
Jun 21, 2001·The American Journal of Geriatric Cardiology·V L Sorrell, N C Nanda
May 15, 2008·Cerebrovascular Diseases·UNKNOWN European Stroke Organisation (ESO) Executive Committee, UNKNOWN ESO Writing Committee
Aug 7, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Chisato IzumiYoshihisa Nakagawa
Mar 31, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Fintan O'RourkeAshfaq Shuaib
Aug 21, 2013·Journal of Atherosclerosis and Thrombosis·Masataka NishigaYoshihisa Nakagawa
Oct 27, 2011·Journal of Atherosclerosis and Thrombosis·Gregory TelmanYoram Agmon
Nov 19, 2013·Heart, Lung & Circulation·Priyanka DhillonSelvanayagam Niranjan
Oct 26, 2012·Current Treatment Options in Neurology·Giuseppe Di PasqualeSimona Gambetti
Sep 24, 2014·Annales de cardiologie et d'angéiologie·C CharbonnelB Livarek
Mar 7, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Marc Fisher, Mark McAllister
Sep 13, 2003·Chest·Richard V MilaniJose A Bernal
Jun 17, 2005·The American Journal of the Medical Sciences·Stamatios Lerakis, William J Nicholson
Sep 4, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Nobl BarazangiS Andrew Josephson
Dec 5, 2009·The American Journal of Medicine·Rejmon Dedaj, William Levy
Mar 13, 2001·Mayo Clinic Proceedings·A OnwuanyiR Parris
Apr 26, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Syed I HussainOsama O Zaidat
Jan 26, 2007·Clinical Neurology and Neurosurgery·Mohamad Bagher SharifkazemiAli Reza Moaref
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Jorge A ZavalaGeoffrey A Donnan
Jan 23, 2008·Journal of Thrombosis and Haemostasis : JTH·F GuerciniM Paciaroni
Feb 14, 2008·Echocardiography·Thenappan ThenappanAssad Movahed

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.