PMID: 6162150Nov 25, 1980Paper

Mobile dispersed genetic element MDG1 of Drosophila melanogaster: transcription pattern

Nucleic Acids Research
Y V IlyinG P Georgiev

Abstract

Virtually the whole region of the mobile dispersed genetic element mdg1 including the direct repeats that frame mdg1 /1/ is transcribed. The end of the transcriptional unit is located within the direct repeat. Although the transcription of mdg1 is symmetric, one direction is transcribed preferentially and is a full-length transcript represented by approximately 29S poly(A)+RNA. Besides it, approximately 15S poly(A)+RNA is present in the cytoplasm of culture cells which corresponds to the 3'-part of 29S RNA and possibly to a small region near the 5'-end of the latter. The major fraction of mdg1 transcripts is present in the fraction of free cytoplasmic RNP particles while only 10-20% are recovered in polysomes. In this respect, mdg1 is similar to mdg3 and quite different from two single-copy genes transcripts of which are almost completely recovered in polysomes. The relationship between mobile dispersed genetic elements and endogeneous viral genomes is discussed.

References

Jan 1, 1978·Cold Spring Harbor Symposia on Quantitative Biology·D J FinneganD S Hogness
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·E Canaani, S A Aaronson
Mar 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·S L McKenzieM Meselson
Mar 25, 1980·Nucleic Acids Research·N A TchurikovG P Georgiev

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Citations

Dec 31, 1980·Molecular Biology Reports·G P GeorgievD A Kramerov
Jun 25, 1991·Nucleic Acids Research·V A CherkassovaY V Ilyin
Apr 9, 2005·Nucleic Acids Research·Alla I KalmykovaVladimir A Gvozdev
Jul 5, 1993·FEBS Letters·N V Lyubomirskaya Ilyin YuV
Jan 1, 1983·Journal of Molecular Evolution·G MartinP Schedl
Mar 1, 1982·CRC Critical Reviews in Biochemistry·Y V Ilyin, G P Georgiev

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