Mobile phone-based evaluation of latent tuberculosis infection: Proof of concept for an integrated image capture and analysis system

Computers in Biology and Medicine
Safa NaraghiTania S Douglas

Abstract

The tuberculin skin test is the most widely used method for detecting latent tuberculosis infection in adults and active tuberculosis in children. We present the development of a mobile-phone based screening tool for measuring the tuberculin skin test induration. The tool makes use of a mobile application developed on the Android platform to capture images of an induration, and photogrammetric reconstruction using Agisoft PhotoScan to reconstruct the induration in 3D, followed by 3D measurement of the induration with the aid of functions from the Python programming language. The system enables capture of images by the person being screened for latent tuberculosis infection. Measurement precision was tested using a 3D printed induration. Real-world use of the tool was simulated by application to a set of mock skin indurations, created by a make-up artist, and the performance of the tool was evaluated. The usability of the application was assessed with the aid of a questionnaire completed by participants. The tool was found to measure the 3D printed induration with greater precision than the current ruler and pen method, as indicated by the lower standard deviation produced (0.3 mm versus 1.1 mm in the literature). There was high...Continue Reading

Citations

Feb 14, 2020·Journal of Medical Internet Research·Yejin LeeAntoine Flahault
Aug 20, 2020·PloS One·Jaydon FaraoTania S Douglas
May 31, 2020·The Journal of Infection·Santino J CapocciMarc C I Lipman
Apr 4, 2021·Children·Marco PappalardoSusanna Esposito

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