Mobile Software as a Medical Device (SaMD) for the Treatment of Epilepsy: Development of Digital Therapeutics Comprising Behavioral and Music-Based Interventions for Neurological Disorders

Frontiers in Human Neuroscience
Pegah AfraGrzegorz Bulaj

Abstract

Digital health technologies for people with epilepsy (PWE) include internet-based resources and mobile apps for seizure management. Since non-pharmacological interventions, such as listening to specific Mozart's compositions, cognitive therapy, psychosocial and educational interventions were shown to reduce epileptic seizures, these modalities can be integrated into mobile software and delivered by mobile medical apps as digital therapeutics. Herein, we describe: (1) a survey study among PWE about preferences to use mobile software for seizure control, (2) a rationale for developing digital therapies for epilepsy, (3) creation of proof-of-concept mobile software intended for use as an adjunct digital therapeutic to reduce seizures, and (4) broader applications of digital therapeutics for the treatment of epilepsy and other chronic disorders. A questionnaire was used to survey PWE with respect to preferred features in a mobile app for seizure control. Results from the survey suggested that over 90% of responders would be interested in using a mobile app to manage their seizures, while 75% were interested in listening to specific music that can reduce seizures. To define digital therapeutic for the treatment of epilepsy, we desig...Continue Reading

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Citations

Feb 11, 2020·Insights Into Imaging·Emmanuel MontagnonAn Tang
May 15, 2020·Journal of Medical Internet Research·Hassane AlamiJean-Paul Fortin
Aug 14, 2019·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Christi J GuerriniAmy L McGuire
Oct 2, 2020·ANZ Journal of Surgery·Lorwai TanGuy Maddern
Nov 28, 2019·SLAS Technology·Agata BlasiakTheodore Kee
May 16, 2020·Frontiers in Public Health·Stefano TribertiGabriella Pravettoni
Jan 9, 2021·Mayo Clinic Proceedings·Anteneh M Feyissa
May 22, 2021·Journal of Neurology·G AbbadessaL Lavorgna
Dec 24, 2021·Journal of the American Medical Informatics Association : JAMIA·Upkar VarshneyShanta R Dube

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

Linux
REDCap Electronic Data Capture
MusicGlove
MoodHacker
SuperBetter
Emotiv
HTML5
reSET®
Akili
WebEase ( Epilepsy Awareness , Support and Education )

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