Mode-specific physical activity and leukocyte telomere length among U.S. adults: Implications of running on cellular aging

Preventive Medicine
Paul D Loprinzi, Eveleen Sng

Abstract

Previous research demonstrates that physical activity participation is associated with longer leukocyte telomere length, with shorter leukocyte telomere length being a hallmark characteristic of cellular aging. What remains under-investigated, however, is whether there is a mode-specific association of physical activity on leukocyte telomere length, which was this study's purpose. Data from the 1999-2002 National Health and Nutrition Examination Survey were used (N=6474 adults analyzed). Leukocyte telomere length was assessed using quantitative polymerase chain reaction. Physical activity was assessed via self-report, with participants classified as meeting physical activity guidelines (≥2000 metabolic equivalent of task-min-month) for 9 separate physical activities, including aerobics (unweighted percent meeting guidelines: 2.98%; n=193), basketball (2.0%; n=129), bicycling (3.71%; n=240), dance (2.30%; n=149), running (3.09%; n=200), stair climbing (1.33%, n=86), swimming (1.85%, n=120), walking (13.53%; n=876), and weight lifting (2.61%; n=169). In a single multivariable linear regression model including the independent variables of age, gender, race-ethnicity, weight status, total cholesterol, C-reactive protein, total meta...Continue Reading

References

May 23, 2003·Cold Spring Harbor Symposia on Quantitative Biology·E H BlackburnH Wang
Sep 2, 2005·Nature Reviews. Genetics·Maria A Blasco
Aug 2, 2008·Journal of the American College of Cardiology·Christian WernerUlrich Laufs
Mar 16, 2011·Journal of Aging Research·Andrew T Ludlow, Stephen M Roth
Feb 4, 2012·American Journal of Epidemiology·Mengmeng DuImmaculata De Vivo
Jun 12, 2013·Cell·Carlos López-OtínGuido Kroemer
Aug 12, 2014·Journal of Physical Activity & Health·Paul D Loprinzi
May 15, 2015·Medicine and Science in Sports and Exercise·Paul D LoprinziElizabeth H Blackburn
Jul 15, 2015·American Journal of Epidemiology·Paul D Loprinzi
Sep 13, 2015·Mayo Clinic Proceedings·Carl J LavieSteven N Blair

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Citations

May 30, 2017·Experimental Gerontology·Aladdin H ShadyabAndrea Z LaCroix
Mar 7, 2017·Medicine and Science in Sports and Exercise·Elisa F OgawaTongjian You
Dec 1, 2017·International Journal of Molecular Sciences·Warrick ChiltonFadi Charchar
Jul 29, 2018·Nature Reviews. Cardiology·Natalie A GudeMark A Sussman
Jan 18, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Melissa Bateson, Daniel Nettle
Mar 17, 2020·Journal of Sports Sciences·Larry A Tucker
Jun 24, 2020·Aging·Maria Donatella SemeraroMarkus Herrmann
Jan 7, 2017·Health Promotion Perspectives·Meghan K Edwards, Paul D Loprinzi
Apr 4, 2021·Biology·Graciela Gavia-GarcíaVíctor Manuel Mendoza-Núñez

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