Abstract
The model-based Karlsburg Diabetes Management System (KADIS®) has been developed as a patient-focused decision-support tool to provide evidence-based advice for physicians in their daily efforts to optimize metabolic control in diabetes care of their patients on an individualized basis. For this purpose, KADIS® was established in terms of a personalized, interactive in silico simulation procedure, implemented into a problem-related diabetes health care network and evaluated under different conditions by conducting open-label mono- and polycentric trials, and a case-control study, and last but not least, by application in routine diabetes outpatient care. The trial outcomes clearly show that the recommendations provided to the physicians by KADIS® lead to significant improvement of metabolic control. This model-based decision-support system provides an excellent tool to effectively guide physicians in personalized decision-making to achieve optimal metabolic control for their patients.
References
Feb 1, 1990·Experimental and Clinical Endocrinology·A RutscherG Albrecht
Oct 1, 1985·IEEE Transactions on Bio-medical Engineering·E SalzsiederE J Freyse
May 1, 1997·Diabetes Care·R C EastmanM Harris
Oct 8, 1999·Diabetic Medicine : a Journal of the British Diabetic Association
Sep 15, 2000·BMJ : British Medical Journal·M CampbellP Tyrer
Dec 6, 2001·International Journal of Medical Informatics·S PlougmannD A Cavan
Nov 6, 2003·Clinical Chemistry and Laboratory Medicine : CCLM·Susan Manley
Aug 25, 2004·Current Medical Research and Opinion·Andrew J PalmerGiatgen A Spinas
Jan 5, 2005·Diabetes Technology & Therapeutics·Eldon D Lehmann
Mar 10, 2005·JAMA : the Journal of the American Medical Association·Amit X GargR Brian Haynes
Jun 3, 2005·Diabetes Technology & Therapeutics·A M AlbisserC Wright
Jun 28, 2006·Diabetes Technology & Therapeutics·Eldon D LehmannS Sabina H Hashmy
Aug 18, 2006·Current Medical Research and Opinion·Massimo Massi-Benedetti
May 1, 2007·Diabetes Care·Petra AugsteinEckhard Salzsieder
Jan 10, 2008·Journal of General Internal Medicine·Basit Chaudhry
Jan 28, 2009·Diabetes Care·Mayer B Davidson
Jul 8, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Richard W Grant, Blackford Middleton
Jul 8, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Anne HolbrookUNKNOWN COMPETE II Investigators
Jan 1, 2010·Implementation Science : IS·Annemie HeselmansDirk Ramaekers
Feb 11, 2010·Journal of Diabetes Science and Technology·David C Klonoff, Mark W True
Citations
Aug 13, 1998·Computer Methods and Programs in Biomedicine·W KellyG Murray
Apr 5, 2013·Diabetes Technology & Therapeutics·Klaus-Dieter KohnertEckhard Salzsieder
Jun 28, 2015·Computer Methods and Programs in Biomedicine·J Jabez ChristopherA Kannan
Mar 4, 2015·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Rudolf ChlupJosef Bartek
Apr 28, 2012·Journal of Diabetes Science and Technology·Sami S KanderianGarry M Steil
Jan 22, 2019·Journal of Diabetes Science and Technology·Lutz VogtEckhard Salzsieder
Jul 28, 2019·Der Internist·A WaschkauJ Steinhäuser
May 19, 2021·Journal of Diabetes Science and Technology·Petra AugsteinEckhard Salzsieder