PMID: 8957957Nov 1, 1996Paper

Model of normal prepubertal growth

Archives of Disease in Childhood
N K ThalangeP E Clayton

Abstract

Growth over the short term is a highly complex non-linear process. Contrasting models of short term growth have been proposed which include periodic growth cycles versus abrupt growth spurts with intervening growth arrest ('saltation and stasis'). The variability of short term growth has been characterised from a study of 46 healthy prepubertal children measured three times a week over one academic year using a combination of descriptive statistical approaches and regression modelling. Growth in childhood over one year is represented by a biphasic process comprising three to six unpredictable growth spurts, each of mean length 56 days (range 13-155 days), separated by periods of stasis (less than or equal to 0.05 cm height increment over more than seven days), each lasting a mean of 18 days (range 8-52 days) and accounting for at least 20% of the period of observation. This is superimposed on strong seasonal trends in growth with a declining growth rate over the autumn months reaching a nadir in midwinter, followed by a growth spurt in the spring. Human growth over short periods is therefore a discontinuous, irregular, and unpredictable process.

References

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Jan 1, 1996·The Journal of Clinical Endocrinology and Metabolism·N K ThalangeP E Clayton

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Citations

Mar 9, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Andrea E Cassidy-BushrowChristine Cole Johnson
Jul 14, 1998·Physiology & Behavior·M HermanussenJ Burmeister
Jun 19, 2004·Annals of Human Biology·S CainoP Adamo
Apr 5, 2014·Journal of Neuroendocrinology·P E ClaytonM Westwood
Jul 28, 2012·Annals of Human Biology·Michelle Lampl
Jun 25, 2016·American Journal of Human Biology : the Official Journal of the Human Biology Council·Alexandra BoucherieSacha Kacki
Feb 9, 2008·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Derek T SmithLucas J Carr
Oct 4, 2000·Pediatric Annals·N J Hopwood
Apr 5, 2014·Journal of the American Society of Nephrology : JASN·Rajiv AgarwalMatthew R Weir
Apr 9, 1998·Annals of Human Biology·J K Wales
May 11, 2006·Annals of Human Biology·Silvia CainoHoracio Lejarraga
Aug 24, 2017·Pediatric Rheumatology Online Journal·Jaime GuzmanLori B Tucker
Nov 10, 2020·Journal of Pediatric Gastroenterology and Nutrition·Meghana N SatheEric First

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