Modeling alterations in sinonasal physiology after skull base surgery

American Journal of Rhinology & Allergy
Dennis O Frank-ItoDavid W Jang

Abstract

Endonasal endoscopic skull base surgery (EESBS) often requires significant alterations in intranasal anatomy. For example, posterior septectomy (PS) with middle turbinate resection (MTR) is frequently performed to provide access to large sellar and clival tumors. However, little is known about the alterations that occur in sinonasal physiology. This study was designed to assess changes in sinonasal physiology after virtually performed endoscopic skull base surgery. Three-dimensional models of the sinonasal passage were created from computed tomography scans in three subjects with varying anatomy: no SD (SD), right anterior SD, and left anterior SD, respectively. Four additional surgery types were performed virtually on each model: endoscopic transsphenoidal approach (ETSA) with small (1 cm) PS (smPS), ETSA with complete (2 cm) PS, ETSA with smPS and right MTR, and ETSA with complete PS and right MTR. Computational fluid dynamics (CFD) simulations were performed on the 3 presurgery and 12 virtual surgery models to assess changes from surgery types. Increased nasal airflow corresponded to amount of tissue removed. Effects of MTR on unilateral airflow allocation were unchanged in subject with no SD, worsened in leftward SD, and re...Continue Reading

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Citations

Oct 19, 2017·The Laryngoscope·Tracy ChengDennis O Frank-Ito
May 12, 2017·American Journal of Rhinology & Allergy·Do Hyun KimSung Won Kim
Nov 19, 2019·Acta Oto-laryngologica·Lifeng LiDemin Han
Jul 25, 2019·Plastic and Reconstructive Surgery. Global Open·Dennis O Frank-ItoJeffrey R Marcus
Jul 29, 2020·International Journal of Oral Science·Bing Shi, Hanyao Huang
Oct 14, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Dennis Onyeka Frank-Ito, Seth Morris Cohen
May 22, 2021·Respiratory Physiology & Neurobiology·Hang LiDennis O Frank-Ito

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Software Mentioned

- CFD14
Fluent
Mimics
ICEM
Mimics16

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