PMID: 16615576Apr 18, 2006Paper

Modeling and phantom studies of ultrasonic wall shear rate measurements using coded pulse excitation.

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Jean K TsouM F Insana

Abstract

Wall shear rate (WSR) is the derivative of blood velocity with respect to vessel radius at the endothelial cell (EC) surface. The product of WSR and blood viscosity is the wall shear stress (WSS) that has been identified as an important factor for atherosclerosis development. High echo signal-to-noise ratio (eSNR) and high spatial resolution are crucial for minimizing the errors in WSR estimates. By transmitting coded pulses with time-bandwidth product greater than one, high eSNR from weak blood scatter can be achieved without increasing instantaneous power or sacrificing spatial resolution. This paper summarizes a series of measurements in a straight tube (5-mm diameter), constant velocity flow phantom using a 10 MHz transducer (60% bandwidth, f/1.5) imaged with a 72 degrees Doppler angle, 125 MHz sampling frequency and 1 kHz pulse repetition frequency. Measurements were made using a frequency-modulated (FM) code, phase-modulated (PM) codes, and uncoded broadband and narrow band pulse transmissions. Both simulation and experimental results show that coded-pulse excitation increases accuracy and precision in WSR estimation for laminar flow over a broad range of peak velocity values when compared to standard pulsing techniques i...Continue Reading

References

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Citations

Jun 10, 2008·The Journal of the Acoustical Society of America·Steven G Kanzler, Michael L Oelze
Jan 28, 2016·Aging and Disease·Xavier Castellon, Vera Bogdanova
Jan 22, 2008·Ultrasound in Medicine & Biology·Jean K TsouMichael F Insana
Jan 20, 2011·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Qiyu Peng, Li-Qun Zhang
Nov 28, 2009·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Jose R SanchezMichael L Oelze
Jul 4, 2009·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Jose R Sanchez, Michael L Oelze
Apr 20, 2007·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Michael L Oelze
Jun 2, 2016·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Alessandro RamalliPiero Tortoli
Aug 10, 2010·Ultrasonic Imaging·Paul LindenMichael L Oelze

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