Modeling axonal degeneration within the anterior visual system: implications for demonstrating neuroprotection in multiple sclerosis

Archives of Neurology
Elliot M FrohmanRobert Zivadinov

Abstract

A major objective in multiple sclerosis therapeutics is to develop strategic targeting of specific injury pathways to provide neuroprotection and potentially even restoration. Here we underscore the potential utility of the anterior visual system for the purpose of modeling neuroprotection in response to novel therapies.

Citations

Dec 2, 2008·Nature Clinical Practice. Neurology·Elliot M FrohmanLaura J Balcer
Sep 10, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·Alexander KlistornerC Yiannikas
Jul 1, 2013·Multiple Sclerosis and Related Disorders·Kristin M Galetta, Laura J Balcer
Dec 1, 2014·Brain : a Journal of Neurology·Laura J BalcerJeffrey A Cohen
Jul 8, 2010·Revue neurologique·C LamirelV Biousse
Feb 10, 2009·Journal of the Neurological Sciences·Jeffrey A Cohen
Sep 2, 2008·Expert Review of Neurotherapeutics·Albert Lo
Feb 1, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Pablo VillosladaAri Green
Dec 19, 2008·Multiple Sclerosis : Clinical and Laboratory Research·A R SalterE M Frohman
Jun 23, 2018·Brain and Behavior·Gro Helen DaleToke Bek
Oct 12, 2013·Annals of Neurology·Iñigo GabilondoPablo Villoslada
Jan 13, 2010·The Neurologist·Sashank PrasadLaura J Balcer
Jan 29, 2011·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Kristin M GalettaLaura J Balcer
Apr 16, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A KardysM Ramanathan
Oct 1, 2010·Continuum : Lifelong Learning in Neurology·Teresa C FrohmanElliot M Frohman
Aug 6, 2019·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Fulvio ZaccagnaTarik F Massoud
Jun 28, 2019·Journal of Hypertension·Susanne JungRoland E Schmieder
Jan 31, 2019·Neurology. Neuroimmunology and Neuroinflammation·Christian CordanoAri J Green
Aug 19, 2014·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Laura J Balcer
Nov 18, 2011·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Randy H Kardon
Feb 23, 2018·Frontiers in Neurology·Alessandro SerraManuela Matta
Dec 20, 2018·Annals of Clinical and Translational Neurology·James D TriplettAlexander Klistorner
May 8, 2021·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Martin Hardmeier, Peter Fuhr

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.