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Modeling bi-modality improves characterization of cell cycle on gene expression in single cells

bioRxiv

Feb 3, 2014

Lucas M DennisRaphael Gottardo

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Abstract

Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on ...read more

Mentioned in this Paper

Gene Expression
Cell Cycle Phase
Research Study
DSP protein, human
Genes
Transcriptome
Genes, cdc
Cell Cycle Arrest
Cell Line, Tumor
Protein Expression
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  • Modeling bi-modality improves characterization of cell cycle on gene expression in single cells

    bioRxiv

    Feb 3, 2014

    Lucas M DennisRaphael Gottardo

    PMID: 990002295

    DOI: 10.1101/002295

    Abstract

    Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on ...read more

    Mentioned in this Paper

    Gene Expression
    Cell Cycle Phase
    Research Study
    DSP protein, human
    Genes

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