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Modeling bi-modality improves characterization of cell cycle on gene expression in single cells

bioRxiv

Feb 3, 2014

Lucas DennisRaphael Gottardo

Abstract

Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on ...read more

Mentioned in this Paper

Cell Cycle Phase
DSP protein, human
Diagnostic Radiology Modality
Lymphocyte
Euphoric Mood
Genes, cdc
Transcriptome
Cell Cycle
Research Study
Cell Line, Tumor
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Modeling bi-modality improves characterization of cell cycle on gene expression in single cells

bioRxiv

Feb 3, 2014

Lucas DennisRaphael Gottardo

PMID: 990002295

DOI: 10.1101/002295

Abstract

Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on ...read more

Mentioned in this Paper

Cell Cycle Phase
DSP protein, human
Diagnostic Radiology Modality
Lymphocyte
Euphoric Mood
Genes, cdc
Transcriptome
Cell Cycle
Research Study
Cell Line, Tumor

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