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Modeling gene expression networks to predict interchromosomal organization during human embryonic stem cell differentiation

bioRxiv

May 10, 2018

Kyle V LasterSteven T Kosak

Abstract

Cellular differentiation occurs through the regulation of lineage-specific gene expression networks that are facilitated by the spatial organization of the genome. Although techniques based on the chromatin conformation capture (3C) approach have yielded intrachromosomal genome-wide int...read more

Mentioned in this Paper

Transcriptional Regulation
Pluripotent Stem Cells
Genome
Genes
Three-dimensional
Regulation of Biological Process
Neurons
Genomic Stability
Radiotherapy, Conformal
Gene Expression
5
2
Paper Details
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Modeling gene expression networks to predict interchromosomal organization during human embryonic stem cell differentiation

bioRxiv

May 10, 2018

Kyle V LasterSteven T Kosak

PMID: 990318899

DOI: 10.1101/318899

Abstract

Cellular differentiation occurs through the regulation of lineage-specific gene expression networks that are facilitated by the spatial organization of the genome. Although techniques based on the chromatin conformation capture (3C) approach have yielded intrachromosomal genome-wide int...read more

Mentioned in this Paper

Transcriptional Regulation
Pluripotent Stem Cells
Genome
Genes
Three-dimensional
Regulation of Biological Process
Neurons
Genomic Stability
Radiotherapy, Conformal
Gene Expression
5
2

Similar Papers Found In These Feeds

PSCs in Development and Disease

Pluripotent stem cells (PSCs) are progenitor cells that can give rise to three basic layers of the body, thus potentially allowing the production of any cells or tissues needed by the body for repair. Here is the latest research on the PSCs in development and disease.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Related Papers

PLoS Computational Biology

Bayesian inference of spatial organizations of chromosomes

PLoS Computational BiologyFebruary 6, 2013
Ming HuJun S Liu
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