PMID: 9848838Dec 16, 1998

Modeling human eye aberrations and their compensation for high-resolution retinal imaging

Optometry and Vision Science : Official Publication of the American Academy of Optometry
L ZhuY Fainman


We introduced a mathematical eye model using Gullstrand's six-surface eye model modified by clinically measured aspherical data to study human eye aberrations and their compensation for high-resolution retinal imaging. Ray tracing was used to characterize aberrations and point spread functions (PSFs) of the eye model. By using the Zernike polynomial decomposition of the calculated pupil function, we quantified the wavefront aberrations. Based on calculated PSFs, we designed optical inverse filters to reduce the aberrations for a large pupil size and improve the resolution. Spherical aberration and oblique astigmatism were found to be in good agreement with published experimental measurements. Spherical aberration and defocus were the most significant aberrations for on-axis imaging, whereas oblique astigmatism and coma combined with spherical aberration and defocus were most significant for off-axis imaging. The best retinal image resolution occurred at 2- to 3-mm pupil diameter. After aberration correction for an 8-mm diameter pupil, the resolutions for on-axis or 9 degrees off-axis imaging points were very close to diffraction-limited resolutions. Over a limited field of view (FOV), retinal image resolution of the eye model c...Continue Reading


Mar 20, 2004·Journal of Cataract and Refractive Surgery·Shin-ichi AoshimaAkira Minakata
Dec 11, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·D Robert IskanderLeo G Carney
Feb 6, 2003·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·George Smith
Jul 19, 2005·The British Journal of Ophthalmology·D U BartschW R Freeman
Jan 25, 2003·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Salvador Bara, Rafael Navarro
Nov 17, 2007·Optics Letters·Stephen A BurnsSalvador Bara
Aug 15, 2002·Journal of Biomedical Optics·Dirk-Uwe BartschW R Freeman

Related Concepts

In Silico
Ocular Refraction

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Related Papers

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
H Burek, W A Douthwaite
Journal of the Optical Society of America. A, Optics, Image Science, and Vision
J SchwiegerlingJ M Miller
Journal of Cataract and Refractive Surgery
S D KlyceN Maeda
© 2021 Meta ULC. All rights reserved