PMID: 9168397May 1, 1997Paper

Modeling of flow in a straight stented and nonstented side wall aneurysm model

Journal of Biomechanical Engineering
M AenisBaruch B Lieber

Abstract

We investigated the changes of flow patterns in a blood vessel with a side wall aneurysm resulting from placement of a stent. Local hemodynamics can be markedly altered by placing an intravascular stent, which covers the orifice of the aneurysm. The alternations in flow patterns can lead to flow stasis in the aneurysmal pouch and promote the formation of a stable thrombus. Furthermore, a porous stent can serve as substrate for neointimal growth and subsequently induce a remodeling of the diseased arterial segment. To examine changes in local hemodynamics due to stent placement, a stented and nonstented aneurysm model was investigated computationally in a three-dimensional configuration using a finite element fluid dynamics program. The finite element model was studied under incompressible, pulsatile, viscous, Newtonian conditions. The fluid dynamic similarity parameter, i.e., the maximum/minimum Reynolds number, was set at about 240/25 based on cross-sectional average instantaneous flow. The Womersley number was set to 2.5. These values are representative of large cerebral arteries. The results of the stented versus the nonstented model show substantial difference sin flow patterns inside the aneurysmal pouch. Flow activity ins...Continue Reading

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Citations

May 1, 1997·Annals of Biomedical Engineering·B B LieberA K Wakhloo
Sep 23, 2008·Neuroradiology·Isabel Wanke, Michael Forsting
Sep 27, 2005·Cardiovascular and Interventional Radiology·Makoto OhtaDaniel A Rüfenacht
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